D-glucose suppression of eating after intra-third ventricle infusion in rat

Physiology & Behavior
K KurataK Fukagawa

Abstract

To clarify the hypophagic action of D-glucose, meal size, postprandial intermeal interval and eating rate were analyzed after infusion of glucose into the third cerebroventricle. The effects of glucose structure modification on feeding modulation were examined by comparing the effects of glucose to those of its epimers, D-mannose, D-allose and D-galactose. Glucose, infused in doses of 6 to 24 mumol, dose relatedly reduced meal size, but did not change other meal parameters. The minimum dose of glucose to induce feeding suppression was between three and 6 mumol. The epimers, at doses of 24 mumol, did not affect food intake or body weight. Drinking patterns and ambulatory activity were not changed by glucose infusion. These findings were consistent with neuronal activity observed in the ventromedial hypothalamic nucleus.

References

May 1, 1979·Physiology & Behavior·M FukushimaT Teranishi
Nov 3, 1975·Biochimica Et Biophysica Acta·A L BetzD D Gilboe
Apr 1, 1985·Proceedings of the Society for Experimental Biology and Medicine·K FujimotoA Simpson
Feb 27, 1973·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H S BachelardO E Pratt
Jan 1, 1974·Pflügers Archiv : European journal of physiology·E ScharrerJ Mayer
Sep 1, 1972·Physiology & Behavior·J Panksepp, D M Nance
Oct 1, 1969·The American Journal of Physiology·G P Smith, A N Epstein
Dec 1, 1971·The American Journal of Physiology·W H Oldendorf
Jul 1, 1970·Physiology & Behavior·J Le Magnen, M Devos
Feb 1, 1971·Proceedings of the Society for Experimental Biology and Medicine·W H Oldendorf
Apr 19, 1969·Nature·Y OomuraM J Wayner
Oct 1, 1983·Physiology & Behavior·K TsutsuiY Hinohara
Jun 1, 1982·Brain Research Bulletin·T Shiraishi, A Simpson
Sep 1, 1981·Physiology & Behavior·T SakataS Nicolaidis

❮ Previous
Next ❯

Citations

Jun 16, 2010·Cellular and Molecular Life Sciences : CMLS·Sabine D JordanJens C Brüning
Jun 23, 2011·Reviews in Endocrine & Metabolic Disorders·Stephanie Sisley, Darleen Sandoval
Nov 10, 1998·Biological Psychiatry·S F Leibowitz, J T Alexander
Jan 4, 2013·PloS One·Darleen SandovalRandy J Seeley
Dec 29, 2013·Lipids in Health and Disease·Isy F de SousaEliane B Ribeiro
Oct 29, 2011·The Journal of Steroid Biochemistry and Molecular Biology·Kadiombo BantubungiBart Staels
Aug 30, 2011·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Sergio PolakofJosé L Soengas
Apr 13, 2010·Brain Research·Catarina Soares PotesThomas Riediger
Jan 1, 1989·Metabolism: Clinical and Experimental·K KurataT Sakata
Jun 15, 2015·Neuroscience·C LeloupL Pénicaud
May 10, 2015·Current Diabetes Reports·Sophie C HamrFrank A Duca
Jan 28, 2015·Journal of Molecular Endocrinology·Juan ZhangGuyu Ho
Nov 20, 2012·Diabetes·Damien LanfrayFabrice Morin
Jul 2, 2008·Diabetes·J Antonio GonzálezDenis Burdakov
Sep 28, 2004·Diabetes·Barry E LevinAmbrose A Dunn-Meynell
Dec 22, 1999·Endocrine Reviews·G A Bray, F L Greenway
Feb 1, 1990·Nutrition Reviews·D A York
Mar 1, 1990·The American Journal of Physiology·S Tsujii, G A Bray

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.