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D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway

Frontiers in Cell and Developmental Biology

Oct 30, 2019

Jinni HongPin-Lan Li

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Abstract

D-ribose levels are demonstrated to be increased in type II diabetes mellitus and increased blood D-ribose is involved in the development of diabetic complications such as diabetic encephalopathy and nephropathy. However, the mechanism mediating the pathogenic role of D-ribose in nephro...read more

Mentioned in this Paper

Diabetes Mellitus, Non-Insulin-Dependent
Enzyme Inhibitors
Gene Deletion
Genes
Interleukin-1 beta
Kidney Diseases
Kidney Failure, Chronic
Laboratory mice
Ribose
Signal Pathways
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D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway

Frontiers in Cell and Developmental Biology

Oct 30, 2019

Jinni HongPin-Lan Li

PMID: 31737627

DOI: 10.3389/fcell.2019.00259

Abstract

D-ribose levels are demonstrated to be increased in type II diabetes mellitus and increased blood D-ribose is involved in the development of diabetic complications such as diabetic encephalopathy and nephropathy. However, the mechanism mediating the pathogenic role of D-ribose in nephro...read more

Mentioned in this Paper

Diabetes Mellitus, Non-Insulin-Dependent
Enzyme Inhibitors
Gene Deletion
Genes
Interleukin-1 beta

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