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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

Science

Nov 21, 1997

K LinC Kenyon

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Abstract

The wild-type Caenorhabditis elegans nematode ages rapidly, undergoing development, senescence, and death in less than 3 weeks. In contrast, mutants with reduced activity of the gene daf-2, a homolog of the insulin and insulin-like growth factor receptors, age more slowly than normal an...read more

Mentioned in this Paper

Fertility
Daf-16b protein, C elegans
Hypokinesia
Caenorhabditis elegans
Transcription, Genetic
Somatomedins
Senility
Etiology
FOXM1 gene
Senescence Function
352
1
Paper Details
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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

Science

Nov 21, 1997

K LinC Kenyon

PMID: 9360933

DOI: 10.1126/science.278.5341.1319

Abstract

The wild-type Caenorhabditis elegans nematode ages rapidly, undergoing development, senescence, and death in less than 3 weeks. In contrast, mutants with reduced activity of the gene daf-2, a homolog of the insulin and insulin-like growth factor receptors, age more slowly than normal an...read more

Mentioned in this Paper

Fertility
Daf-16b protein, C elegans
Hypokinesia
Caenorhabditis elegans
Transcription, Genetic
Somatomedins
Senility
Etiology
FOXM1 gene
Senescence Function
352
1

Feeds With Similar Papers

Science eTOC

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

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Paper Details
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  • Citations780
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  • References
  • Citations780
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