Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: a randomized, controlled pilot study.

The Journal of Urology
Deborah A WingJudith H Chung

Abstract

We compared the effects of daily cranberry juice cocktail to those of placebo during pregnancy on asymptomatic bacteriuria and symptomatic urinary tract infections. A total of 188 women were randomized to cranberry or placebo in 3 treatment arms of A-cranberry 3 times daily (58), B-cranberry at breakfast then placebo at lunch and dinner (67), and C-placebo 3 times daily (63). After 27.7% (52 of 188) of the subjects were enrolled in the study the dosing regimens were changed to twice daily dosing to improve compliance. There were 27 urinary tract infections in 18 subjects in this cohort, with 6 in 4 group A subjects, 10 in 7 group B subjects and 11 in 7 group C subjects (p = 0.71). There was a 57% and 41% reduction in the frequency of asymptomatic bacteriuria and all urinary tract infections, respectively, in the multiple daily dosing group. However, this study was not sufficiently powered at the alpha 0.05 level (CI 0.14-1.39 and 0.22-1.60, respectively, incidence rate ratios). Of 188 subjects 73 (38.8%) withdrew, most for gastrointestinal upset. These data suggest there may be a protective effect of cranberry ingestion against asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. Further studies are p...Continue Reading

References

Feb 1, 1989·American Journal of Epidemiology·K StenqvistC Svanborg-Edén
Mar 1, 1985·American Journal of Epidemiology·G A McGradyD R Peterson
Mar 1, 1984·Clinical Obstetrics and Gynecology·P Duff
Oct 6, 1997·Infectious Disease Clinics of North America·T F Patterson, V T Andriole
Aug 22, 2001·Obstetrics and Gynecology Clinics of North America·L C Gilstrap, S M Ramin
Jun 19, 2002·JAMA : the Journal of the American Medical Association·Amy B Howell, Betsy Foxman
Feb 20, 1965·Lancet·P KINCAID-SMITH, M BULLEN
Feb 1, 1960·Archives of Internal Medicine·E H KASS
May 12, 2007·Molecular Nutrition & Food Research·Ruth G Jepson, Jonathan C Craig
Feb 7, 2008·The Cochrane Database of Systematic Reviews·R G Jepson, J C Craig

❮ Previous
Next ❯

Citations

Apr 29, 2009·Antimicrobial Agents and Chemotherapy·Meng LiGail D Anderson
Dec 10, 2013·BMC Complementary and Alternative Medicine·Kristine HeitmannLone Holst
May 16, 2009·Drugs·David R P Guay
Dec 15, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cibele Barbosa-CesnikBetsy Foxman
Nov 22, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jarmo SaloTero Kontiokari
Jul 30, 2014·Physical Medicine and Rehabilitation Clinics of North America·Lance L Goetz, Adam P Klausner
Mar 31, 2010·Journal of Perinatology : Official Journal of the California Perinatal Association·A O GalãoJ G L Ramos
Sep 11, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Satoshi TakahashiTetsuro Matsumoto
Feb 26, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Stefano SalvatoreMarco Torella
Feb 4, 2011·Research in Microbiology·Zeynep Erdogan-YildirimMarkus Zeitlinger
Nov 5, 2015·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Deborah A WingMichael Nageotte
Oct 18, 2015·The Urologic Clinics of North America·Alexander P Glaser, Anthony J Schaeffer
Sep 16, 2009·The Journal of Obstetrics and Gynaecology Research·Faustino R Pérez-LópezPeter Chedraui
Oct 12, 2010·Journal of the American Geriatrics Society·Manisha Juthani-MehtaKalpana Gupta
Mar 17, 2016·BMC Complementary and Alternative Medicine·D A KennedyH Nordeng
Jan 9, 2014·Phytotherapy Research : PTR·Antonella SmeriglioDomenico Trombetta
Aug 30, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·G DanteF Facchinetti
Feb 19, 2014·Current Opinion in Obstetrics & Gynecology·Giulia DanteFabio Facchinetti
Feb 12, 2013·Clinical Nursing Research·Cha-Nam Shin
Aug 8, 2015·The Cochrane Database of Systematic Reviews·Fiona M Smaill, Juan C Vazquez
Oct 27, 2018·Nature Reviews. Urology·Néha SihraSachin Malde
May 25, 2010·Journal of Clinical Gastroenterology·Ruggero RossiBrenno Canovi
Nov 26, 2019·The Cochrane Database of Systematic Reviews·Fiona M Smaill, Juan C Vazquez
Sep 29, 2019·World Journal of Urology·Liang G QuNathan Lawrentschuk
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Ruth G JepsonJonathan C Craig
Jan 1, 2009·Journal of Dietary Supplements·Ted Wilson, Brent A Bauer
Jan 31, 2020·Frontiers in Pharmacology·Sílvia M IllamolaElena Y Enioutina
May 28, 2019·Anaesthesia and Intensive Care·Peter Ca KamIan D Douglas
Nov 21, 2020·Future Journal of Pharmaceutical Sciences·Sarita Das

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.