Daily cumulative load and body mass index alter knee cartilage response to running in women.

Gait & Posture
Elora C Brenneman WilsonMonica R Maly

Abstract

It is unknown whether a greater accumulation of knee load over a typical day is related to how cartilage responds to an acute bout of loading. This information may clarify the role of habitual activity on cartilage function. Is there a relationship between change in tibial and femoral cartilage thickness, volume, and T2 relaxation time following running with daily cumulative knee load in women? Secondarily, is there a relationship between cartilage change following running and the statistical interaction of body mass index (BMI) and daily steps? Participants (n = 15) completed gait analyses and wore an accelerometer over a week. Daily cumulative knee load was the statistical interaction between tibial compressive joint reaction force (JRF) impulse with the average number of daily steps measured using accelerometry. Magnetic resonance imaging scans were acquired before and immediately after 15-min of treadmill running. Changes in tibial and femoral cartilage thickness, volume, and T2 relaxation time were calculated. Multiple linear regressions tested the associations of cartilage change outcomes with: baseline (thickness, volume, T2), JRF impulse, steps, and the interaction JRF impulse*steps. Secondarily, BMI was substituted for...Continue Reading

References

Sep 7, 2007·Medicine and Science in Sports and Exercise·Raymond C Browning, Rodger Kram
Dec 20, 2007·Medicine and Science in Sports and Exercise·Richard P TroianoMargaret McDowell
Jul 12, 2011·Annals of the Rheumatic Diseases·Kim L BennellRana S Hinman
Dec 31, 2011·Gait & Posture·Katherine M SteeleScott L Delp
Jun 26, 2012·The American Journal of Sports Medicine·Karupppasamy SubburajSharmila Majumdar
Sep 18, 2013·Medicine and Science in Sports and Exercise·Ross H MillerKevin J Deluzio
Oct 15, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·V MezhovA E Wluka
Aug 16, 2016·The American Journal of Sports Medicine·Kate A TimminsKimberley L Edwards
Feb 6, 2017·Journal of Biomechanics·Anthony A GattiMonica R Maly
Mar 23, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nicholas M BrissonMonica R Maly
Sep 14, 2017·Annals of Biomedical Engineering·Adrian K M LaiJames M Wakeling
Oct 20, 2018·Arthritis Research & Therapy·Amber T CollinsLouis E DeFrate
Oct 22, 2019·Science Advances·Ming-Feng HsuehVirginia B Kraus

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.