Daily feeding of diclazuril top dress pellets in foals reduces seroconversion to Sarcocystis neurona

The Veterinary Journal
N PusterlaP A Conrad

Abstract

Thirty-three foals from a farm with a high exposure rate to Sarcocystis neurona were assigned to either an untreated or a diclazuril-treated group. Treated foals received daily 0.5 mg/kg of diclazuril pellets from 1 to 12 months of age. Monthly blood was tested for IgG against S. neurona using the indirect fluorescent antibody test. Following ingestion of colostral antibodies to S. neurona, there was a steady and continuous decline in seroprevalence to S. neurona until foals from both groups reached weaning age. Thereafter, the untreated foal group showed a significant increase in monthly seroprevalence compared to the diclazuril-treated foal group. The difference in temporal seroprevalence could be explained by the successful reduction of S. neurona infection in foals receiving a daily low-dose diclazuril.

References

Oct 24, 2000·Journal of the American Veterinary Medical Association·W J SavilleT E Wittum
Feb 13, 2003·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Paulo C DuarteIan A Gardner
Mar 4, 2008·American Journal of Veterinary Research·Robert J MackayTom J Kennedy
Oct 21, 2014·Journal of Veterinary Pharmacology and Therapeutics·L HunyadiN Pusterla

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