Daily online localization using implanted fiducial markers and its impact on planning target volume for carcinoma prostate

Journal of Cancer Research and Therapeutics
Robin KhosaLalit Sharma

Abstract

Aim of the study was to assess prostate motion on daily basis with respect to setup and to compare the shifts based on bony anatomy and gold fiducial markers. Gold fiducial markers were inserted in prostate under U/S guidance and daily portal images were taken and compared with digitally reconstructed images, both using bony landmarks and fiducial markers as reference. A dose of 2 MU was given for two orthogonal images daily. The mean and standard deviation of displacement using gold seeds and bone were calculated. Systematic and random errors were generated. The planning target volume (PTV) was calculated using the Van Herk formula. A total of 180 portal images from 10 patients were studied. The mean displacement along x, y and z axes was 1.67 mm, 3.58 mm, and 1.76 mm using fiducial markers and 2.12 mm, 3.47 mm, and 2.09 mm using bony landmarks, respectively. The mean internal organ motion was 1.23 mm (+1.45), 3.11 mm (+2.69 mm); and 1.87 mm (+1.67 mm) along x, y and z axes, respectively. The PTV to account for prostate motion if daily matching was not done was 4.64 mm, 10.41 mm and 4.40 mm along lateral, superoinferior, and anteroposterior directions, respectively. If bony landmarks were used for daily matching, margins of 3....Continue Reading

References

Jun 1, 1991·International Journal of Radiation Oncology, Biology, Physics·R K Ten HakenA S Lichter
Oct 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J M CrookB Esche
Feb 1, 1996·International Journal of Radiation Oncology, Biology, Physics·V G AlthofH J te Loo
Jul 15, 1996·International Journal of Radiation Oncology, Biology, Physics·V RudatM Wannenmacher
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·J HanleyG J Kutcher
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·M van HerkJ V Lebesque
Oct 6, 2000·International Journal of Radiation Oncology, Biology, Physics·M R StoreyI Rosen
Mar 2, 2002·International Journal of Radiation Oncology, Biology, Physics·G PangJ A Rowlands
Sep 5, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Joep C Stroom, Ben J M Heijmen
Jul 23, 2003·International Journal of Radiation Oncology, Biology, Physics·Darren J LittleDeborah A Kuban
Oct 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Michael G HermanBernard F King

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Citations

Sep 19, 2014·Technology in Cancer Research & Treatment·Maria F ChanJoseph O Deasy
May 9, 2013·Journal of Applied Clinical Medical Physics·Qingyang ShangPing Xia
Jan 22, 2015·Advanced Healthcare Materials·Rasmus I JølckThomas L Andresen

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