Daily peritoneal ultrafiltration predicts patient and technique survival in anuric peritoneal dialysis patients

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Xinghui LinJiaqi Qian

Abstract

Maintenance dialysis therapy is the only way to remove excess fluid in patients with anuric end-stage renal disease. The optimal ultrafiltration (UF) volume in patients on peritoneal dialysis (PD) remains controversial. We retrospectively analysed a cohort of 86 prevalent anuric PD patients followed up for a median of 25.3 months (range, 6 to 54 months). Clinical and PD parameters were recorded yearly. Kaplan-Meier analysis and Cox proportional hazards models were used to identify risk factors of mortality and technique failure in patients with a UF >/=1 L/24 h or <1 L/24 h. When compared to those with a UF <1 L/24 h, patients with a UF >/=1 L/24 h had significantly higher haemoglobin levels (101.9 +/- 20.5 vs 89.3 +/- 20.2 g/L, P < 0.05) and tended to be younger (55.0 +/- 12.5 vs 60.6 +/- 16.1 years, P = 0.10). Also, while Kt/V and CCr were stable over time, UF decreased significantly over the study period (baseline, 1205.5 +/- 327.3 ml/24 h vs after 3 years, 870.6 +/- 439.8 ml/24 h; P < 0.001). Using Kaplan-Meier analysis, patients with baseline UF <1 L/24 h had significantly worse outcome (survival, 27.2 +/- 3.9 vs 42.4 +/- 1.9 months; P < 0.001). In multivariate Cox regression analysis, age, time-dependent UF volume and ser...Continue Reading

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Citations

May 31, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Joan-Carles TrullàsUNKNOWN Spanish HIV Infection in Dialysis Study Group
Jan 4, 2012·Blood Purification·Xinghui LinJiaqi Qian
Feb 27, 2014·Journal of Nephrology·Giovambattista VirgaMaurizio Nordio
Jun 29, 2012·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Thiane Gama-AxelssonAbdul Rashid Qureshi
May 31, 2018·Journal of the American Society of Nephrology : JASN·Johann MorelleOlivier Devuyst
Apr 21, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Anne-Lorraine ClauseJohann Morelle
Dec 15, 2015·The International Journal of Artificial Organs·Stanley Fan, Andrew Davenport
Nov 2, 2019·Canadian Journal of Kidney Health and Disease·Benoit Imbeault, Annie-Claire Nadeau-Fredette
Feb 11, 2021·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Johann MorelleSimon Davies

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