Daily Physical Activity Predicts Frailty Development Among Community-Dwelling Older Japanese Adults

Journal of the American Medical Directors Association
Atsumu YukiHidenori Arai

Abstract

This study examined the association between frailty development and physical activity including the number of steps, the time of light-intensity physical activity (LPA) with <3.0 metabolic equivalents (METs), and the time of moderate- to vigorous-intensity physical activity (MVPA) with ≥3.0 METs in community-dwelling older Japanese adults. Study subjects were 401 older adults at the baseline examination (April 2000-May 2002) who participated at least once in the follow-up examination of the longitudinal study of aging. Their 1787 cumulative data points (mean number of repeat visits, 3.5) were used for analysis. The number of steps, time of LPA, and time of MVPA were recorded at baseline using a uniaxial accelerometer. Frailty was defined according to 5 frailty criteria: shrinking, exhaustion, low physical activity, low grip strength, and slow gait speed. The fully adjusted odds ratio for frailty among subjects walking <5000 steps was 1.85 [95% confidence interval (CI), 1.10-3.11]. The fully adjusted odds ratio for frailty among subjects with MVPA for <7.5 minutes was 1.80 (95% CI, 1.05-3.09). No significant association was observed between frailty and LPA. The risk for developing frailty was substantially lower in older people ...Continue Reading

References

Sep 19, 2000·Medicine and Science in Sports and Exercise·B E AinsworthA S Leon
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
May 22, 2003·Pharmacology, Biochemistry, and Behavior·A S IvyA A Russo-Neustadt
May 2, 2006·Obesity·Rod K DishmanMichael J Zigmond
Dec 20, 2007·Medicine and Science in Sports and Exercise·Richard P TroianoMargaret McDowell
Jun 15, 2010·Medicine and Science in Sports and Exercise·Mark D PetersonPaul M Gordon
Jun 18, 2011·Medicine and Science in Sports and Exercise·Barbara E AinsworthArthur S Leon
Sep 27, 2012·BMC Geriatrics·Ding-Cheng Derrick ChanKen N Kuo
Nov 13, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Matteo CesariUNKNOWN LIFE Study Group
Apr 3, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Samuel J E LucasDamian M Bailey
Apr 30, 2015·Journal of the American Medical Directors Association·Hiroyuki ShimadaTakao Suzuki
Nov 30, 2016·Journal of Cachexia, Sarcopenia and Muscle·Ding-Cheng Derrick ChanKen N Kuo
Aug 23, 2017·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Olga TheouKenneth Rockwood
Oct 5, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·John R BestUNKNOWN Health, Aging and Body Composition Study
Jan 9, 2018·Annals of Internal Medicine·Andrea TrombettiUNKNOWN LIFE Study Investigators
Apr 3, 2018·Geriatrics & Gerontology International·Atsumu YukiHiroshi Shimokata
Jun 29, 2018·International Journal of Environmental Research and Public Health·Venicius Dantas da SilvaJair Sindra Virtuoso Júnior

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Citations

Mar 21, 2020·Journal of the American Geriatrics Society·Xuxi ZhangHein Raat
Sep 12, 2020·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Tara O'BrienDonna Hathaway
Jul 8, 2020·Journal of the American Medical Directors Association·Kazuki UemuraHiroshi Okamoto
Dec 4, 2020·Journal of the American Geriatrics Society·Daiki WatanabeKyoto-Kameoka Study Group
Feb 26, 2021·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·Kazuki UemuraHiroshi Okamoto
Mar 1, 2021·Progress in Cardiovascular Diseases·Elizabeth C LeffertsDuck-Chul Lee
Jul 10, 2021·Journal of Neuroengineering and Rehabilitation·Grainne VavasourDaniel Kelly
Sep 26, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Amal A WanigatungaJennifer A Schrack

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