PMID: 8604666Jan 1, 1996Paper

Daily supplements of vitamin A (8.4 mumol, 8000 IU) improve the vitamin A status of lactating Indonesian women

The American Journal of Clinical Nutrition
S A TanumihardjoJ A Olson

Abstract

The vitamin A statuses of lactating Indonesian women (n = 23) starting at 1-3 mo after delivery were determined at three monthly intervals (times 1, 2, and 3) during lactation and then again (time 4) after they had ingested vitamin A capsules (8.4 mumol, 8000 IU) daily for 35 d. Vitamin A status was determined by using the modified-relative-dose-response (MRDR) test and serum retinol concentrations. The mean MRDR ratio in these women rose from 0.084 +/- 0.047 (time 1) to 0.099 +/- 0.045 (time 2) and then to 0.100 +/- 0.054 (time 3). After supplementation the mean MRDR ratio fell to 0.040 +/- 0.021 (time 4) (P < 0.0001). Mean serum retinol concentrations at the first three times were 0.94 +/- 0.23, 0.87 +/- 0.20, and 0.80 +/- 0.20 mumol/L, but then rose to 1.10 +/- 0.31 mumol/L at time 4 (P < 0.04). After supplementation mean MRDR values and mean serum retinol concentrations were 60% lower and 38% higher, respectively, than those just before supplementation, MRDR values better distinguished the vitamin A statuses of the women than did serum retinol concentrations. Mean hemoglobin values increased during the study from 118 +/- 9 g/L at time 1 to 122 +/- 6 g/L at time 4 (P = 0.0187). The mean hematocrit also rose from 0.35 +/- 0.0...Continue Reading

Citations

Jan 1, 1998·American Journal of Human Biology : the Official Journal of the Human Biology Council·Peter R BertiWilma J Berti
Apr 1, 2004·European Journal of Clinical Nutrition·V Singh, K P West
Nov 21, 2007·Food and Nutrition Bulletin·John MasonMa Antonia Tuazon
Apr 25, 2020·Experimental Biology and Medicine·Jesse SheftelSherry A Tanumihardjo
Oct 2, 2020·Current Developments in Nutrition·Bryan M GannonSaurabh Mehta
Jul 1, 2011·The American Journal of Clinical Nutrition·Sherry A Tanumihardjo
Feb 9, 2005·The American Journal of Clinical Nutrition·Ashley R Valentine, Sherry A Tanumihardjo
Jan 18, 2018·Critical Reviews in Food Science and Nutrition·Marcela de Sá Barreto da CunhaSandra Fernandes Arruda
Jan 6, 2004·The Journal of Nutrition·Sherry A Tanumihardjo
Nov 2, 2020·Advances in Nutrition·Jesse Sheftel, Sherry A Tanumihardjo
Jul 21, 2021·Food and Nutrition Bulletin·Kesso Gabrielle van ZutphenAlida Melse-Boonstra

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