Daily variation in antioxidant enzymes and lipid peroxidation in lungs of a tropical bird Perdicula asiatica: role of melatonin and nuclear receptor RORα

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Rajesh Kumar Kharwar, C Haldar

Abstract

The wild animals are exposed in nature to more oxidative stress than any laboratory animals. Studies on oxidative stress of brain, liver and kidney are quite common while very less reports are available on respiratory system when it is the most susceptible organ to various stressors. We checked the oxidative stress of lung tissue of a wild seasonally breeding bird Perdicula asiatica by noting down the daily variation in antioxidant enzymes (superoxide dismutase and catalase) levels, lipid peroxidation in terms of malondialdehyde level and total antioxidant status during reproductively active (RAP) and inactive phase (RIP). On the other hand melatonin has been accepted as free radical scavenger acting via receptor (nuclear receptor) or non receptor pathway. To pin point the role of melatonin in regulation of antioxidant enzymes via non receptor mediated pathway in lungs of bird, we checked variation in the nuclear melatonin receptor RORα. Antioxidant enzymes (superoxide dismutase and catalase) exhibited a marked 24h rhythm in lungs being high during night time and coincided almost with the peak of melatonin and total antioxidant status where as malondialdehyde level and nuclear receptor RORα showed inverse relationship with all ...Continue Reading

References

Jun 1, 1972·Analytical Biochemistry·A K Sinha
Jan 1, 1993·Journal of Pineal Research·G J Maestroni
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
Nov 4, 2000·Journal of Biomedical Science·R J ReiterE Gitto
Mar 10, 2001·Biochemistry. Biokhimii︠a︡·A N Smirnov
Apr 6, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·C C SudhakumariB Senthilkumaran
Dec 12, 2002·Cellular and Molecular Life Sciences : CMLS·J C MayoC Rodriguez
Dec 18, 2002·Journal of Pineal Research·M AllegraM A Livrea
Apr 1, 2003·Endocrine Research·Vanesa MartínCarmen Rodríguez
Dec 17, 2003·Journal of Pineal Research·Carmen RodriguezRussel J Reiter
Mar 1, 1995·Archives of Gerontology and Geriatrics·C PieriR Recchioni
Jan 30, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Shiv Shankar Singh, Chandana Haldar
Feb 16, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·R K Kharwar, C Haldar

❮ Previous
Next ❯

Citations

Apr 8, 2014·Pharmacology, Biochemistry, and Behavior·Surbhi Gupta, Bhupesh Sharma
Nov 21, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Shu-Chun Chuang, Jiun-Hong Chen
Mar 17, 2016·World Journal of Biological Chemistry·Biswaranjan PaitalGagan Bihari Nityananda Chainy
Apr 1, 2019·Journal of Pineal Research·Ting GaoYaoxing Chen
May 21, 2019·Frontiers in Cellular Neuroscience·Maria M Benedetto, Maria A Contin
Apr 18, 2018·Reproduction in Domestic Animals = Zuchthygiene·H S TalpurL Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.