Damage to temporo-parietal cortex decreases incidental activation of thematic relations during spoken word comprehension.

Neuropsychologia
Daniel Mirman, Kristen M Graziano

Abstract

Both taxonomic and thematic semantic relations have been studied extensively in behavioral studies and there is an emerging consensus that the anterior temporal lobe plays a particularly important role in the representation and processing of taxonomic relations, but the neural basis of thematic semantics is less clear. We used eye tracking to examine incidental activation of taxonomic and thematic relations during spoken word comprehension in participants with aphasia. Three groups of participants were tested: neurologically intact control participants (N=14), individuals with aphasia resulting from lesions in left hemisphere BA 39 and surrounding temporo-parietal cortex regions (N=7), and individuals with the same degree of aphasia severity and semantic impairment and anterior left hemisphere lesions (primarily inferior frontal gyrus and anterior temporal lobe) that spared BA 39 (N=6). The posterior lesion group showed reduced and delayed activation of thematic relations, but not taxonomic relations. In contrast, the anterior lesion group exhibited longer-lasting activation of taxonomic relations and did not differ from control participants in terms of activation of thematic relations. These results suggest that taxonomic and ...Continue Reading

References

Feb 7, 1998·Proceedings of the National Academy of Sciences of the United States of America·S L Thompson-SchillM J Farah
Apr 29, 1998·Brain : a Journal of Neurology·G RobinsonL Cipolotti
Jun 24, 2000·Neuropsychologia·S BozeatJ R Hodges
Feb 6, 2004·Psychological Review·Timothy T RogersKaralyn Patterson
Nov 19, 2004·Brain : a Journal of Neurology·Sebastian J Crutch, Elizabeth K Warrington
Jan 12, 2005·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Douglas L NelsonThomas A Schreiber
Dec 17, 2005·Journal of Cognitive Neuroscience·Joseph W KableAnjan Chatterjee
Feb 16, 2006·Journal of Experimental Psychology. Learning, Memory, and Cognition·Eiling Yee, Julie C Sedivy
Apr 28, 2006·Psychological Review·Matthew M Botvinick, David C Plaut
Jul 4, 2006·Brain : a Journal of Neurology·Elizabeth Jefferies, Matthew A Lambon Ralph
Aug 30, 2006·Neuropsychology·Juliana V Baldo, Nina F Dronkers
Sep 23, 2006·Journal of Cognitive Neuroscience·Joseph W Kable, Anjan Chatterjee
Aug 24, 2007·Journal of Cognitive Neuroscience·Denise H WuAnjan Chatterjee
Nov 21, 2007·Nature Reviews. Neuroscience·Karalyn PattersonTimothy T Rogers
Dec 28, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marian E BerryhillIngrid R Olson
Aug 30, 2008·Cognition·Sabrina Simmons, Zachary Estes
Oct 14, 2008·Neurobiology of Learning and Memory·Ingrid R Olson, Marian Berryhill
Dec 9, 2008·Journal of Memory and Language·Daniel MirmanJames S Magnuson
Jan 2, 2009·Proceedings of the National Academy of Sciences of the United States of America·Tatiana T SchnurSharon L Thompson-Schill
Jun 10, 2009·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Christopher R ButlerMaria-Luisa Gorno-Tempini
Jun 23, 2009·Cognitive Science·Christopher M O'ConnorKen McRae
Sep 12, 2009·Memory & Cognition·Daniel Mirman, James S Magnuson
Nov 28, 2009·Brain : a Journal of Neurology·Myrna F SchwartzH Branch Coslett
Sep 2, 2010·Brain : a Journal of Neurology·Solène KalénineHarry Branch Coslett
Mar 23, 2011·Journal of Experimental Psychology. General·Eiling YeeSharon L Thompson-Schill
Apr 27, 2011·Journal of Experimental Psychology. Human Perception and Performance·Anne Pier Salverda, Gerry T M Altmann
May 5, 2011·Proceedings of the National Academy of Sciences of the United States of America·Myrna F SchwartzH Branch Coslett
Aug 25, 2011·Journal of Cognitive Neuroscience·Malathi ThothathiriMyrna F Schwartz
Oct 18, 2011·Trends in Cognitive Sciences·Jeffrey R Binder, Rutvik H Desai
Dec 29, 2011·Journal of Experimental Psychology. General·Daniel Mirman, Kristen M Graziano
Mar 28, 2012·Journal of Experimental Psychology. Learning, Memory, and Cognition·Solène KalénineLaurel J Buxbaum

❮ Previous
Next ❯

Citations

May 8, 2013·Journal of Cognitive Neuroscience·Daniel Mirman, Kristen M Graziano
Sep 12, 2015·Experimental Brain Research·Francesco De BellisLuigi Trojano
Apr 18, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jingyi Geng, Tatiana T Schnur
Feb 25, 2015·Journal of Neuropsychology·Paul Hoffman
Jun 1, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Laura M Skipper-KallalIngrid R Olson
Apr 17, 2015·Nature Communications·Daniel MirmanMyrna F Schwartz
Jan 15, 2015·Neuropsychologia·Gwyneth A LewisGregory L Murphy
May 6, 2016·Brain and Language·Nazbanou NozariSharon L Thompson-Schill
Jul 9, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Solène Kalénine, Laurel J Buxbaum
Jul 16, 2019·Journal of Clinical and Experimental Neuropsychology·Catherine MerckSolène Kalénine
Dec 17, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Elizabeth JefferiesJonathan Smallwood
Aug 28, 2020·Brain Structure & Function·Lorenzo VercesiGabriele Miceli
Jun 8, 2018·Cerebral Cortex·Gwyneth A LewisGregory L Murphy
Aug 18, 2021·Human Brain Mapping·Graham FlickLiina Pylkkänen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.