Damage/recovery by additive on lipid membrane as a mimicry of human stratum corneum

Langmuir : the ACS Journal of Surfaces and Colloids
Yan ZhuTakashi Oka

Abstract

The effects of sodium dodecyl sulfate (SDS) on the model lipid membrane of human stratum corneum, composed of three main lipids of ceramide III, palmitic acid, and cholesterol, have been examined as a function of exposure period. Cholesterol first got to elute, palmitic acid followed it late, and the remaining solid was mainly ceramide III. The removal of lipids influenced the configurational structure of remaining lipid and the intralayer structure of lamellae. Monitoring of structural reorganization in the damaged membrane was carried out on the recovering procedure of palmitic acid and cholesterol. Both lipids were penetrated in the damaged membrane and recovered mostly the configurational lipid structure and the lamellar structure. Especially, it can be noted that cholesterol is more effective than palmitic acid on recovery.

References

Sep 1, 1992·The Journal of Investigative Dermatology·K HaradaS Yamamoto
Nov 1, 1991·The Journal of Investigative Dermatology·K P WilhelmH I Maibach
May 1, 1986·The Journal of Investigative Dermatology·A W Fulmer, G J Kramer
Jan 1, 1981·Pharmacology & Therapeutics·H J Yardley, R Summerly
Jan 1, 1982·The British Journal of Dermatology·G M GrayH J Yardley
Aug 1, 1994·The Journal of Investigative Dermatology·C L GayM L Francoeur
Sep 1, 1997·The Journal of Investigative Dermatology·M PonecA M Mommaas
May 13, 1998·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·E E LawsonH G Edwards
Dec 14, 1999·The Journal of Investigative Dermatology·R R WarnerK J Stone
Feb 17, 2000·International Journal of Pharmaceutics·E BárányM Lodén

❮ Previous
Next ❯

Citations

Dec 24, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Sang-Wook LeeDaeyeon Lee
Aug 3, 2010·Colloids and Surfaces. B, Biointerfaces·Xiaojuan WangTooru Okamoto
Nov 29, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Barbora SkolováKateřina Vávrová

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.