PMID: 375768Feb 1, 1979Paper

Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium

Anaesthesia
C B Collier

Abstract

A single oral dose of dantrolene (100--150 mg) given at least 2 hr pre-operatively has been found to reduce significantly the strength of muscular fasciculations, the hyperkalaemia and the incidence of muscle pains following suxamethonium (from 56 to 4%) in a series of forty-eight patients compared with controls. The biceps EMG of the fasciculations was unchanged by dantrolene; the incidence of troublesome side effects was low (9%) and there did not appear to be any alteration in the duration of action of suxamethonium.

References

May 1, 1978·Anaesthesia·C B Collier
Sep 1, 1976·European Journal of Pharmacology·H E Statham, C J Duncan
Apr 1, 1977·Anesthesiology·A Baraka
Aug 1, 1977·Anaesthesia and Intensive Care·K L Austin, M A Denborough
Mar 27, 1975·Nature·L Brocklehurst
Jul 1, 1975·Anesthesiology·G A Gronert, R A Theye
Feb 1, 1971·Southern Medical Journal·S B ChyatteB A Bergman
Oct 7, 1971·The New England Journal of Medicine·J F RyanA I Hyman
Apr 3, 2003·Journal of Basic and Clinical Physiology and Pharmacology·Mehmet Emin BüyükokuroğluAkçahan Gepdiremen
Jan 1, 1957·Anesthesiology·J B DILLOND B TAYLOR

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Citations

Mar 1, 1994·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J E Cannon
Jan 1, 1984·Canadian Anaesthetists' Society Journal·B A Britt
May 1, 1987·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·B MelnickT E Rudy
Jan 29, 2000·Anaesthesia·S F Wong, F Chung
Jul 28, 2004·Anesthesiology·Steven P CohenSalahadin Abdi
Feb 1, 1990·Anaesthesia and Intensive Care·S M Yentis
Feb 1, 1980·Anaesthesia and Intensive Care·C B Collier
Jan 1, 1988·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J R SalassaA K Brown

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