Darcy Permeability of Hollow Fiber Membrane Bundles Made from Membrana Polymethylpentene Fibers Used in Respiratory Assist Devices

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Shalv P MadhaniWilliam J Federspiel

Abstract

Hollow fiber membranes (HFMs) are used in blood oxygenators for cardiopulmonary bypass or in next generation artificial lungs. Flow analyses of these devices is typically done using computational fluid dynamics (CFD) modeling HFM bundles as porous media, using a Darcy permeability coefficient estimated from the Blake-Kozeny (BK) equation to account for viscous drag from fibers. We recently published how well this approach can predict Darcy permeability for fiber bundles made from polypropylene HFMs, showing the prediction can be significantly improved using an experimentally derived correlation between the BK constant (A) and bundle porosity (ε). In this study, we assessed how well our correlation for A worked for predicting the Darcy permeability of fiber bundles made from Membrana polymethylpentene (PMP) HFMs, which are increasingly being used clinically. Swatches in the porosity range of 0.4 to 0.8 were assessed in which sheets of fiber were stacked in parallel, perpendicular, and angled configurations. Our previously published correlation predicted Darcy within ±8%. A new correlation based on current and past measured permeability was determined: A = 497ε - 103; using this correlation measured Darcy permeability was within ...Continue Reading

References

Feb 17, 2000·Artificial Organs·M J GartnerW R Wagner
Jun 26, 2002·Artificial Organs·Kenneth L GageWilliam R Wagner
Mar 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Brian FillJeff Ma
Sep 25, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jutta ArensUlrich Steinseifer
Oct 22, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Tao ZhangZhongjun J Wu
May 15, 2012·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Begum AkayKeith E Cook
Aug 29, 2012·Journal of Membrane Science·Heather E PacellaWilliam J Federspiel
Oct 30, 2012·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Rebecca E ScheweKeith E Cook
Jun 14, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Laurance LequierRobert H Bartlett
Apr 23, 2014·Artificial Organs·R Garrett JeffriesWilliam J Federspiel
Nov 29, 2014·Thoracic Surgery Clinics·Martin Strueber

❮ Previous
Next ❯

Citations

Dec 15, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ryan A OrizondoWilliam J Federspiel
Dec 4, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Andreas KaeslerJutta Arens
Jun 14, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Alex J ThompsonRonald B Hirschl

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.