PMID: 11931085Apr 5, 2002Paper

Dark adaptation in age-related macular degeneration: relationship to the fellow eye

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
R HaimoviciA C Bird

Abstract

Abnormalities of dark adaptation have been documented in patients with age-related macular degeneration (AMD), but the relationship with the various forms of this disorder has not been studied systematically. Dark-adapted retinal sensitivities and kinetics of dark adaptation were studied using a Humphrey visual field analyzer adapted for these purposes in patients over 64 years of age. One eye per patient was studied. Study eyes had a normal visual acuity and macular drusen only. The fellow eye was categorized as follows: group I, pigment epithelial detachments and tears of the retinal pigment epithelium (RPE); group II, choroidal neovascularization; and group III, drusen only. The results of psychophysical tests of the study eyes (group I and II and one eye of group III patients) were compared with one another and with older patients without evidence of AMD (group IV). Retinal sensitivity was found to be most consistently abnormal nearest the fovea. The time course of dark adaptation was prolonged beyond 45 min in 10/11 patients (91%) in group I, 6/10 patients (60%) in group II, and 6/10 (60%) in group III and 1/11 (9%) in group IV. In a high proportion of patients with visual loss from AMD in one eye, the fellow eye shows abn...Continue Reading

Citations

Dec 23, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Birgit Lorenz, Markus N Preising
Feb 9, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Faran SabetiTed Maddess
May 15, 2003·Survey of Ophthalmology·Jayakrishna AmbatiAnthony P Adamis
Feb 26, 2011·Human Molecular Genetics·Venkata R M ChavaliRadha Ayyagari
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Mar 21, 2009·Survey of Ophthalmology·Kumari NeelamStephen Beatty
Aug 2, 2008·Ophthalmology·Gui-Shuang YingUNKNOWN Complications of Age-related Macular Degeneration Prevention Trial Research Group
Sep 8, 2007·Ophthalmology·Cynthia OwsleyMark Clark
Nov 1, 2005·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jan Lovie-Kitchin, Beatrix Feigl
Oct 27, 2010·Vision Research·Cynthia Owsley
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Jun 28, 2005·Neurobiology of Aging·Janos FeherCorrado Balacco Gabrieli
Jan 9, 2015·Journal of Clinical Medicine·Michael B GorinSteven Nusinowitz
Nov 7, 2018·Investigative Ophthalmology & Visual Science·Humza J TahirIan J Murray
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Jul 6, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Lei LiuHarold E Bedell
Apr 8, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Gregory R JacksonMitchell G Brigell
Nov 15, 2017·Current Eye Research·S NusinowitzM Gorin
Nov 30, 2021·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Matt TrinhLisa Nivison-Smith

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