Dark-light change of iris parameters and related factors among American Caucasians, American Chinese, and Mainland Chinese

Current Eye Research
Dandan WangShan Lin

Abstract

To assess the distribution of dark-light changes in iris features and associated factors amongst American Caucasians, American Chinese and mainland Chinese aged 40 years and over. Four gender- and age-matched cohorts: Caucasians, American Chinese, Southern Chinese and Northern Chinese comprised the study population. Anterior segment optical coherence tomography (ASOCT) images were acquired under dark and light conditions. Customized software was used to calculate iris thickness at 750 μm from the scleral spur (IT750), iris curvature (ICurv), iris area (IArea), and pupil diameter (PD) from ASOCT images. Data from 121, 124, 121 and 120 subjects were available for American Caucasian, American Chinese, Southern and Northern Chinese subjects respectively. Caucasians had significantly less dark-light change (Δ) of IT750 and greater ΔPD than Chinese. When using multiple linear regression analyses, the inter-ethnic difference for ΔIT750 was independent of age, gender, refractive error, anterior chamber width and axial length. After controlling for ΔPD, ΔICurv was found to be inversely associated with age (β = -0.001, P = 0.001). Independent predictors of greater ΔPD included younger age (β = -0.02, P = 0.001), Caucasian ethnicity (β = ...Continue Reading

References

Oct 24, 2001·The British Journal of Ophthalmology·P J Foster, G J Johnson
Oct 24, 2003·International Ophthalmology Clinics·C Richard BlakeDeepak P Edward
Jan 27, 2006·Current Opinion in Ophthalmology
Mar 23, 2006·Current Opinion in Ophthalmology·James C Tsai
May 14, 2008·Archives of Ophthalmology·Raghavan LavanyaTin Aung
Feb 2, 2010·Ophthalmology·Harry A Quigley
Jun 10, 2010·The British Journal of Ophthalmology·B-S WangT Aung
Nov 3, 2010·Ophthalmology·Monisha E NongpiurTin Aung
Jul 29, 2011·Clinical & Experimental Ophthalmology·Dandan WangShan Lin

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Citations

May 2, 2013·Investigative Ophthalmology & Visual Science·Ye Elaine WangShan C Lin
Jan 1, 2016·Current Opinion in Ophthalmology·Dajiang Wang, Shan Lin

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