DART-Orbitrap MS: a novel mass spectrometric approach for the identification of phenolic compounds in propolis

Analytical and Bioanalytical Chemistry
Elena S ChernetsovaGertrud E Morlock

Abstract

This is the first direct analysis in real-time mass spectrometry (DART-MS) study of propolis and a first study on the analysis of bee products using high-resolution DART-MS (DART-HRMS). Identification of flavonoids and other phenolic compounds in propolis using direct analysis in real-time coupling with Orbitrap mass spectrometry (DART-Orbitrap MS) was performed in the negative ion mode for minimizing the matrix effects, while the positive ion mode was used for the confirmation of selected compounds. Possible elemental formulae were suggested for marker components. The duration of one sample analysis by DART-MS analysis lasted ca. 30 s, and all benefits of high-resolution mass spectrometry were used upon data processing using the coupling of DART with the Orbitrap mass spectrometer. The possibility for scanning analysis of dried propolis extract spots on a planar porous surface was investigated in the heated gas flow of the DART ion source with adjustable angle. As an independent method, the approach of scanning analysis is of high interest and of future potential for confirmation of the results obtained from liquid sample analysis. Scanning analysis is highly promising for further development in the bioanalytical field due to ...Continue Reading

References

Apr 15, 2005·Analytical Chemistry·Robert B CodyH Dupont Durst
Jul 16, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Adrian Bolarinwa, Jakob Linseisen
Oct 26, 2010·Rapid Communications in Mass Spectrometry : RCM·Milena ZachariasovaJana Hajslova
Apr 19, 2011·Analytical Chemistry·Glenn A HarrisFacundo M Fernández
Jul 14, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Tomas CajkaJana Hajslova
Jul 19, 2011·Rapid Communications in Mass Spectrometry : RCM·Elena S ChernetsovaGertrud E Morlock

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Citations

Sep 17, 2013·Analytical and Bioanalytical Chemistry·Jürgen H Gross
Jan 11, 2013·Chemical Reviews·María Eugenia MongeFacundo M Fernández
Dec 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Ewelina SzliszkaWojciech Król
Jul 30, 2014·Analytical and Bioanalytical Chemistry·Anastasia AlbertCarsten Engelhard
Jan 1, 2016·Journal of Chromatography. a·André de VilliersHarald Pasch
Jun 9, 2015·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Hamide Z SenyuvaEbru Ates Sarikaya
Jul 15, 2015·Journal of the American Society for Mass Spectrometry·Hongmei YangShuying Liu
Jul 6, 2015·Analytical and Bioanalytical Chemistry·Clara IbáñezAlejandro Cifuentes
Jul 30, 2014·Analytical Chemistry·Gertrud E Morlock, Ines Klingelhöfer
May 16, 2015·Mass Spectrometry Reviews·Tianyang GuoTianwei Tan
Mar 10, 2018·Environmental Science and Pollution Research International·Priscila Aparecida MilaniElma Neide Vasconcelos Martins Carrilho
Sep 24, 2015·Rapid Communications in Mass Spectrometry : RCM·Elena S Chernetsova, Gertrud E Morlock
Jun 5, 2014·European Journal of Mass Spectrometry·Jürgen H Gross
Dec 6, 2020·Rapid Communications in Mass Spectrometry : RCM·Xiaoping ZhangKonstantin Chingin
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Magdalena RatajczakJan Matysiak

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