Data-driven directions for effective footwear provision for the high-risk diabetic foot

Diabetic Medicine : a Journal of the British Diabetic Association
M L J ArtsSicco A Bus

Abstract

Custom-made footwear is used to offload the diabetic foot to prevent plantar foot ulcers. This prospective study evaluates the offloading effects of modifying custom-made footwear and aims to provide data-driven directions for the provision of effectively offloading footwear in clinical practice. Eighty-five people with diabetic neuropathy and a recently healed plantar foot ulcer, who participated in a clinical trial on footwear effectiveness, had their custom-made footwear evaluated with in-shoe plantar pressure measurements at three-monthly intervals. Footwear was modified when peak pressure was ≥ 200 kPa. The effect of single and combined footwear modifications on in-shoe peak pressure at these high-pressure target locations was assessed. All footwear modifications significantly reduced peak pressure at the target locations compared with pre-modification levels (range -6.7% to -24.0%, P < 0.001). The metatarsal heads were most frequently targeted. Repositioning an existing (trans-)metatarsal pad in the shoe insole (-15.9% peak pressure relief), applying local cushioning to the insole (-15.0%) and replacing the insole top cover with Plastazote (-14.2%) were the most effective single modifications. Combining a new Plastazote t...Continue Reading

References

Mar 1, 1996·Diabetes Research and Clinical Practice·H KatoS Torii
Oct 17, 1998·Diabetes Care·R G FrykbergA Veves
Dec 29, 2000·Foot & Ankle International·C van SchieP R Cavanagh
Apr 24, 2001·Diabetes Care·R DahmenA F Hoeksma
Jan 28, 2003·Diabetes Care·Stephan F E Praet, Jan-Willem K Louwerens
Jul 2, 2004·The New England Journal of Medicine·Andrew J M BoultonLoretta Vileikyte
Jun 24, 2005·American Journal of Physical Medicine & Rehabilitation·Wei-Li HsiXin-Xian Lee
Jul 5, 2005·Diabetologia·M H Nabuurs-FranssenN C Schaper
Nov 15, 2006·Diabetes/metabolism Research and Reviews·Giovanni A MatricaliChantal Mathieu
May 20, 2008·Journal of the American Podiatric Medical Association·Angel Camp FaulíCésar Orgilés Barceló
Feb 18, 2012·The International Journal of Lower Extremity Wounds·Loredana RizzoAlberto Piaggesi
May 1, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·R WaaijmanS A Bus
Aug 24, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·M L J ArtsS A Bus
Apr 8, 2014·Diabetes Care·Roelof WaaijmanSicco A Bus

❮ Previous
Next ❯

Citations

Jan 27, 2018·Journal of Foot and Ankle Research·Jaap J van NettenPaul R Wraight
Jan 21, 2020·Diabetes/metabolism Research and Reviews·Jaap J van NettenSicco A Bus
Mar 17, 2020·Diabetes/metabolism Research and Reviews·Sicco A BusUNKNOWN International Working Group on the Diabetic Foot
Apr 30, 2019·Journal of Diabetes Science and Technology·Peter A LazzariniBijan Najafi
Dec 18, 2019·Diabetes/metabolism Research and Reviews·Sicco A BusTessa Busch-Westbroek
Jan 21, 2020·Diabetes/metabolism Research and Reviews·Jaap J van NettenSicco A Bus
Aug 25, 2016·Plastic and Reconstructive Surgery·Sicco A Bus
Dec 8, 2020·Journal of Diabetes and Its Complications·Petra JonesDavid Webb
Feb 4, 2021·Endocrinology, Diabetes & Metabolism·Richard CollingsJoanne Paton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.