Data interchange using i2b2

Journal of the American Medical Informatics Association : JAMIA
Jeffrey G KlannShawn N Murphy

Abstract

Reinventing data extraction from electronic health records (EHRs) to meet new analytical needs is slow and expensive. However, each new data research network that wishes to support its own analytics tends to develop its own data model. Joining these different networks without new data extraction, transform, and load (ETL) processes can reduce the time and expense needed to participate. The Informatics for Integrating Biology and the Bedside (i2b2) project supports data network interoperability through an ontology-driven approach. We use i2b2 as a hub, to rapidly reconfigure data to meet new analytical requirements without new ETL programming. Our 12-site National Patient-Centered Clinical Research Network (PCORnet) Clinical Data Research Network (CDRN) uses i2b2 to query data. We developed a process to generate a PCORnet Common Data Model (CDM) physical database directly from existing i2b2 systems, thereby supporting PCORnet analytic queries without new ETL programming. This involved: a formalized process for representing i2b2 information models (the specification of data types and formats); an information model that represents CDM Version 1.0; and a program that generates CDM tables, driven by this information model. This appr...Continue Reading

References

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Apr 5, 2014·Journal of the American Medical Informatics Association : JAMIA·Jeffrey G KlannShawn N Murphy
May 14, 2014·Journal of the American Medical Informatics Association : JAMIA·Kenneth D MandlShawn N Murphy
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Citations

Oct 27, 2017·Journal of the American Medical Informatics Association : JAMIA·Hossein EstiriShawn N Murphy
Mar 30, 2019·Journal of the American Medical Informatics Association : JAMIA·Hossein EstiriShawn N Murphy
Oct 9, 2019·Journal of the American Medical Informatics Association : JAMIA·Nicholas J DobbinsSean D Mooney
Nov 27, 2019·Journal of the American Medical Informatics Association : JAMIA·Alon GevaKenneth D Mandl
Jul 23, 2019·Clinical Pharmacology and Therapeutics·Sebastian SchneeweissDorothee B Bartels
Aug 8, 2018·Journal of the American Medical Informatics Association : JAMIA·Jeffrey G KlannShawn N Murphy
Mar 27, 2019·Journal of Medical Internet Research·Seo Jeong ShinRae Woong Park
Aug 21, 2020·Healthcare Informatics Research·Shorabuddin SyedKevin W Sexton
Jun 27, 2019·BMC Medical Informatics and Decision Making·Mark D DaneseRyan Duryea
Jun 28, 2019·Learning Health Systems·Jessica M MalenfantJeffrey S Brown
Feb 19, 2021·Journal of Medical Internet Research·Isaac S KohaneTianxi Cai
Feb 11, 2021·Journal of the American Medical Informatics Association : JAMIA·Jeffrey G KlannShawn N Murphy
Jul 1, 2018·Annual Review of Biomedical Data Science·Jamie R RobinsonJoshua C Denny

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Software Mentioned

BioPortal
PCORnet
CDM
Structured Query Language ( SQL )
SHRINE
i2b2
SCILHS

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