Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis

Data in Brief
Tatyana BelyaevaMikhail Churnosov

Abstract

Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed.

Methods Mentioned

BETA
genotyping

Software Mentioned

Sequenom MassARRAY
HaploReg
Haploview

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
M FransenJ P Thyssen
Primary Care Respiratory Journal : Journal of the General Practice Airways Group
Colin R Simpson, Aziz Sheikh
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Maaz S MohiuddinDonald Y M Leung
© 2021 Meta ULC. All rights reserved