Dataset of complete genome assembly and analysis of mycobacterium tuberculosis strain SIT745/EAI1-MYS

Data in Brief
Mohammad AbdullahAzian Harun

Abstract

In this dataset, we report the genome assembly and data analysis of Mycobacterium tuberculosis strain SIT745/EAI1-MYS. Previously, this strain was isolated from a Malaysian patient with extra-pulmonary tuberculosis, and identification of this strain is done by spoligotype patterns with fifteen known Shared International Type (SITs). Further analysis showed that this strain has a remarkable phylogeographical specificity for Malaysia. Based on the National Center for Biotechnology Information (NCBI) nucleotide database information, the complete genome consists of 150 contigs with various sequence lengths and was not assembled. In this assembly, the aforementioned contigs along with reference sequence from Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis strain AF2122/97 was used for gap closures, were assembled into a single circular chromosome length of approximately 4.42 Mega bases (Mb) with an average GC content of 65.6%. The single circular chromosome was shown to contain 4,009 protein-coding sequences, 3 ribosomal RNAs, 45 transfer RNAs, and 12 superclasses distributed with 277 subsystems which constitute nearly 1900 genes, respectively. The genome information will provide fundamental knowledge of this organis...Continue Reading

Associated Datasets

Apr 27, 2020·Azian HarunSuharni Mohamad

References

Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Oct 14, 2004·Bioinformatics·Paul Stothard, David S Wishart
Jun 28, 2016·Nucleic Acids Research·Tatiana TatusovaJames Ostell
Dec 3, 2016·Nucleic Acids Research·Alice R WattamRick L Stevens
Apr 25, 2018·Saudi Journal of Biological Sciences·Ali Nour-NeamatollahiAhmadreza Bahrmand
Jan 7, 2020·Molecular Biology and Evolution·Glen StecherSudhir Kumar

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Datasets Mentioned

BETA
CP046529

Methods Mentioned

BETA
proteomic profiling

Software Mentioned

SnapGene
PhyML
PATRIC
BLAST
TBpred
BioEdit
MEGA ( Molecular Evolutionary Genetics Analysis )
CLUSTAL
CGView

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