Day to Day Variability and Reliability of Blood Oxidative Stress Markers within a Four-Week Period in Healthy Young Men

Journal of Biomarkers
Allan H GoldfarbJ D Labban

Abstract

The present study aimed to determine the day to day variability and reliability of several blood oxidative stress markers at rest in a healthy young cohort over a four-week period. Twelve apparently healthy resistance trained males (24.6 ± 3.0 yrs) were tested over 7 visits within 4 weeks with at least 72 hrs between visits at the same time of day. Subjects rested 30 minutes prior to blood being obtained by vacutainer. Results. The highest IntraClass correlations (ICC's) were obtained for protein carbonyls (PC) and oxygen radical absorbance capacity (ORAC) (PC = 0.785 and ORAC = 0.780). Cronbach's α reliability score for PC was 0.967 and for ORAC was 0.961. The ICC's for GSH, GSSG, and the GSSG/TGH ratio ICC were 0.600, 0.573, and 0.570, respectively, with Cronbach's α being 0.913, 0.904, and 0.903, respectively. Xanthine oxidase ICC was 0.163 and Cronbach's α was 0.538. Conclusions. PC and ORAC demonstrated good to excellent reliability while glutathione factors had poor to excellent reliability. Xanthine oxidase showed poor reliability and high variability. These results suggest that the PC and ORAC markers were the most stable and reliable oxidative stress markers in blood and that daily changes across visits should be consi...Continue Reading

References

May 1, 1978·Analytical Biochemistry·S T Ohnishi, J K Barr
Dec 1, 1988·The American Journal of Physiology·H M AlessioR G Cutler
Jan 1, 1994·Methods in Enzymology·R L LevineE Shacter
Feb 1, 1994·Journal of Clinical and Experimental Neuropsychology·D V Cicchetti
May 1, 1996·Kidney International·V Witko-SarsatB Descamps-Latscha
Jun 11, 1999·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·A H Goldfarb
Jun 29, 2000·Journal of Hypertension·N S DhallaT Netticadan
Feb 21, 2006·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Tongjian YouMichael J McKenzie
Jun 13, 2006·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·I KatoZora Djuric
Aug 16, 2006·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·W K Al-DelaimyH B Bueno-de-Mesquita
Jan 8, 2008·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Neelam AzadVal Vallyathan
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
May 15, 2009·International Journal of Environmental Research and Public Health·Athanasios ValavanidisKonstantinos Fiotakis
Mar 25, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Xiaoyan WuXiao-Ou Shu
Jul 10, 2010·International Journal of Sports Medicine·R DeminiceA A Jordão
Aug 7, 2010·Medicine and Science in Sports and Exercise·Allan H GoldfarbLauren A Chambers
Jun 13, 2013·Clinical Biochemistry·Lee StonerJames Faulkner
Jul 12, 2013·Oxidative Medicine and Cellular Longevity·Alexandra Muñoz, Max Costa
Mar 15, 2014·Electrolyte & Blood Pressure : E & BP·Young Sun Kang
Apr 3, 2014·Physiological Reviews·Asima BhattacharyyaSheila E Crowe
May 29, 2014·International Journal of Environmental Research and Public Health·Chung-Yen LuYi-Chun Chen
Jun 25, 2014·Oxidative Medicine and Cellular Longevity·Peter X ShawYan Chen

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Citations

Feb 11, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Paul BălănescuCristian Băicuş

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