Day-to-day variation in iron status indexes is similar for most measures in elderly women with and without rheumatoid arthritis

Journal of the American Dietetic Association
C J Lammi-KeefeN R Haley

Abstract

To determine the day-to-day variation in biochemical measures of iron status in a group of elderly women with rheumatoid arthritis compared with a group of healthy elderly women. Venous blood samples were collected from each subject on 3 nonconsecutive days during a 2-week study period; subjects had fasted overnight. Variability in hemoglobin level, hematocrit value, serum iron concentration, total iron-binding capacity, transferrin saturation, serum ferritin concentration, and plasma transferrin receptor level was determined. Two groups of women, one with rheumatoid arthritis (n=10) and another that was apparently healthy (n=10). Variance component analysis was used to estimate the biological variation (sigma square day) and analytic variation (sigma square rep) for each iron index. The coefficient of variation (CV) for each variance component was calculated: coefficient of biological variation = CV day, coefficient of analytic variation = CV rep, and coefficient of a single future determination = CV fd. The CV rep for all iron indexes was smaller than the CV day in both groups. The CV day was considerably higher for serum iron concentration and for transferrin saturation than for the other indexes in both groups (16.6% and 16...Continue Reading

References

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Citations

Jul 4, 2006·The American Journal of Psychiatry·Daniel A GormanBradley S Peterson
Mar 1, 2006·Indian Journal of Clinical Biochemistry : IJCB·J V GnanouA V Kurpad
Sep 1, 2009·World Journal of Pediatrics : WJP·Cara Lianne OoiGuido Filler
Feb 19, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Yves Beguin
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Jul 2, 2002·American Journal of Clinical Pathology·Jane C DaleAlan R Zinsmeister
Oct 3, 2002·Journal of Clinical Laboratory Analysis·Robert F RitchieWendy Y Craig
Dec 13, 2019·Scandinavian Journal of Clinical and Laboratory Investigation·Arvind Kumar GuptaNilotpal Chowdhury
Oct 4, 2005·The British Journal of Nutrition·Anita BelzaInge Tetens
Mar 27, 2003·Sports Medicine·Poul Thirup

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