Daylight photodynamic therapy in Scotland

Scottish Medical Journal
Helen CordeyS H Ibbotson

Abstract

Chronic sun-induced dysplastic skin changes (actinic keratoses) are extremely common in fair-skinned people in Scotland. These changes are a major cause of morbidity and may develop into skin cancer. Actinic keratoses are often extensive and pose a therapeutic challenge as field-directed treatment is required for chronic disease management. One such treatment approach is hospital-based photodynamic therapy, which is a well-established treatment in Scotland for actinic keratoses, using a photosensitiser pro-drug and red LED light irradiation. However, photodynamic therapy using daylight as the activating light source is increasingly and effectively used in continental Europe, but had not been explored in Scotland until we initiated this in 2013. We report our experience of daylight photodynamic therapy in 64 patient-treatment courses and demonstrate that this can be an effective, well-tolerated treatment, which is liked by patients. Our most recent data show that most patients (73%) achieved clearance or at least a good response to treatment and had high levels of satisfaction with daylight photodynamic therapy. Daylight exposure measurements indicated that treatment is feasible in Scotland between April to September. Daylight p...Continue Reading

References

Aug 14, 2003·Photodermatology, Photoimmunology & Photomedicine·C ClarkS H Ibbotson
Oct 24, 2008·The British Journal of Dermatology·C A MortonUNKNOWN British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group
Feb 22, 2011·Photodiagnosis and Photodynamic Therapy·Sasi Kiran AttiliSally Ibbotson
Jan 4, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·S R WiegellL R Braathen
Nov 28, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·C A MortonL R Braathen
Nov 28, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·C A MortonL R Braathen

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Citations

Mar 29, 2019·The British Journal of Dermatology·L J McLellanE Eadie
Sep 25, 2019·Pharmaceuticals·Paul O'MahoneySally Ibbotson
Sep 24, 2020·Photodermatology, Photoimmunology & Photomedicine·Iman KotbSally H Ibbotson
Mar 21, 2019·The British Journal of Dermatology·P O'MahoneyE Eadie
Nov 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chaw-Ning LeeTak-Wah Wong

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