DCIS of the breast: The value of preoperative MRI

Journal of Medical Imaging and Radiation Oncology
Anthony James DoyleRobyn Oldfield

Abstract

Ductal carcinoma in situ (DCIS) of the breast is commonly treated surgically. The intent of this study was to evaluate whether preoperative MRI could add to mammography in predicting the extent of the disease. A series of patients with DCIS attending our surgical clinic for preoperative assessment were offered MRI as part of a prospective study. The extent of the disease indicated by mammography and MRI was compared with histopathology after definitive treatment. The null hypothesis was that MRI does not add to mammography in accurately predicting disease extent. Fifty patients make up the basis of this report. Mammography was concordant with the pathology in 31/50. MRI and mammography combined were concordant in 43/50. This is a statistically significant difference (P = 0.01, Fisher's exact test). Upstaging to mastectomy by MRI was correct in 7/8 patients, but downstaging was correct in only 2/4. The null hypothesis is rejected. MRI does add to mammography in accurately predicting the extent of DCIS. Upstaging by MRI is usually reliable.

References

Nov 10, 2009·European Journal of Radiology·C Marcotte-BlochC Chapellier
Mar 11, 2010·Annals of Surgical Oncology·Lisa R AllenThomas G Frazier
Jul 14, 2011·Annals of Surgical Oncology·Benjamin T MillerTodd M Tuttle
Mar 1, 2012·European Radiology·Eline E DeurlooKenneth G A Gilhuijs
Aug 23, 2012·Annals of Surgical Oncology·Kathryn L DavisKari Rosenkranz
Jun 13, 2013·European Journal of Radiology·Chiara ZuianiMassimo Bazzocchi
Jul 16, 2013·World Journal of Surgical Oncology·Brigid K KilleleaDonald R Lannin
Jan 8, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nehmat HoussamiLawrence J Solin
Mar 15, 2014·The Lancet Oncology·Susan Mayor
May 23, 2014·AJR. American Journal of Roentgenology·Janice S SungElizabeth A Morris
Aug 28, 2014·International Journal of Surgery·Gianni Antonio Della CorteAntonello Accurso

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Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

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