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De novo assembly of human genomes with massively parallel short read sequencing

Genome Research

Dec 19, 2009

Ruiqiang LiJun Wang

Abstract

Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assemb...read more

Mentioned in this Paper

Genome
African Continental Ancestry Group
Sequencing
Sequence Determinations, DNA
Korean Race
Cdna Microarrays
Genome, Human
Determination, Sequence Homology
Human Genome Diversity Project
DNA Sequence
1
1472
1
6
Paper Details
References
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  • Citations1241
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  • References32
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De novo assembly of human genomes with massively parallel short read sequencing

Genome Research

Dec 19, 2009

Ruiqiang LiJun Wang

PMID: 20019144

DOI: 10.1101/gr.097261.109

Abstract

Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assemb...read more

Mentioned in this Paper

Genome
African Continental Ancestry Group
Sequencing
Sequence Determinations, DNA
Korean Race
Cdna Microarrays
Genome, Human
Determination, Sequence Homology
Human Genome Diversity Project
DNA Sequence
1
1472
1
6

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Genome Research

Velvet: algorithms for de novo short read assembly using de Bruijn graphs

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Daniel R Zerbino, Ewan Birney
Genome Research

ABySS: a parallel assembler for short read sequence data

Genome ResearchMarch 3, 2009
Jared T SimpsonInanç Birol
Paper Details
References
  • References32
  • Citations1241
1234
  • References32
  • Citations1241
12345...
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