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De novo assembly of human genomes with massively parallel short read sequencing

Genome Research

Feb 1, 2010

Rui Qiang LiJun Wang

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Abstract

Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assemb...read more

Mentioned in this Paper

Genome
Genome, Human
Determination, Sequence Homology
DNA Sequence
Cdna Microarrays
Sequence Determinations, DNA
Human Genome Diversity Project
African Continental Ancestry Group
Korean Race
Sequencing
1
1442
1
6
Paper Details
References
    • References32
    • Citations1120
    • References32
    • Citations1120
  • De novo assembly of human genomes with massively parallel short read sequencing

    Genome Research

    Feb 1, 2010

    Rui Qiang LiJun Wang

    PMID: 20019144

    DOI: 10.1101/gr.097261.109

    Abstract

    Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assemb...read more

    Mentioned in this Paper

    Genome
    Genome, Human
    Determination, Sequence Homology
    DNA Sequence
    Cdna Microarrays
    1
    1442
    1
    6
    Paper Details
    References
    • References32
    • Citations1120
    • References32
    • Citations1120
  • Get paper from

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