Deafness in cochlear and auditory nerve disorders

Handbook of Clinical Neurology
Kathryn Hopkins

Abstract

Sensorineural hearing loss is the most common type of hearing impairment worldwide. It arises as a consequence of damage to the cochlea or auditory nerve, and several structures are often affected simultaneously. There are many causes, including genetic mutations affecting the structures of the inner ear, and environmental insults such as noise, ototoxic substances, and hypoxia. The prevalence increases dramatically with age. Clinical diagnosis is most commonly accomplished by measuring detection thresholds and comparing these to normative values to determine the degree of hearing loss. In addition to causing insensitivity to weak sounds, sensorineural hearing loss has a number of adverse perceptual consequences, including loudness recruitment, poor perception of pitch and auditory space, and difficulty understanding speech, particularly in the presence of background noise. The condition is usually incurable; treatment focuses on restoring the audibility of sounds made inaudible by hearing loss using either hearing aids or cochlear implants.

Citations

Jul 25, 2019·Alzheimer Disease and Associated Disorders·Alexander Chern, Justin S Golub
Jan 15, 2020·Npj Aging and Mechanisms of Disease·Mustafa N OkurVilhelm A Bohr
Jan 7, 2021·Npj Aging and Mechanisms of Disease·Mustafa N OkurVilhelm A Bohr
May 6, 2021·Stem Cells·Majlinda LakoMiodrag Stojkovic

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