Dean-flow-coupled elasto-inertial three-dimensional particle focusing under viscoelastic flow in a straight channel with asymmetrical expansion-contraction cavity arrays

Biomicrofluidics
D YuanW H Li

Abstract

In this paper, 3D particle focusing in a straight channel with asymmetrical expansion-contraction cavity arrays (ECCA channel) is achieved by exploiting the dean-flow-coupled elasto-inertial effects. First, the mechanism of particle focusing in both Newtonian and non-Newtonian fluids was introduced. Then particle focusing was demonstrated experimentally in this channel with Newtonian and non-Newtonian fluids using three different sized particles (3.2 μm, 4.8 μm, and 13 μm), respectively. Also, the effects of dean flow (or secondary flow) induced by expansion-contraction cavity arrays were highlighted by comparing the particle distributions in a single straight rectangular channel with that in the ECCA channel. Finally, the influences of flow rates and distances from the inlet on focusing performance in the ECCA channel were studied. The results show that in the ECCA channel particles are focused on the cavity side in Newtonian fluid due to the synthesis effects of inertial and dean-drag force, whereas the particles are focused on the opposite cavity side in non-Newtonian fluid due to the addition of viscoelastic force. Compared with the focusing performance in Newtonian fluid, the particles are more easily and better focused in...Continue Reading

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Citations

Feb 23, 2017·Analytical Chemistry·Sei Hyun YangYoung Seok Song
Aug 15, 2018·Lab on a Chip·Sei Hyun YangYoung Seok Song
Jan 18, 2018·Lab on a Chip·Dan YuanWeihua Li
Dec 7, 2019·Current Pharmaceutical Design·Katarzyna KluszczyńskaMarkus Düchler
May 28, 2019·Biomicrofluidics·Mohammad Amin RaoufiMajid Ebrahimi Warkiani
Aug 7, 2021·Micromachines·Mahmud Kamal RaihanXiangchun Xuan
Feb 9, 2018·Chemical Reviews·Deborah HuberGovind V Kaigala
Sep 13, 2021·Electrophoresis·Sharath Narayana IyengarAman Russom

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