Deanxit relieves symptoms in a patient with jackhammer esophagus: A case report

World Journal of Gastrointestinal Endoscopy
Jin-Ying LiLie-Xin Liang

Abstract

Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett's esophagus on endoscopy and high-resolution manometry demonstrated jackhammer esophagus with esophagogastric junction outflow obstruction. The patient was treated with proton pump inhibitor and nifedipine but without resolution of his symptoms. He was followed up to assess the efficacy of treatment with deanxit (flupentixol + melitracen). Dysphagia and chest pain resolved during the therapeutic trial and efficacy was maintained on maintenance treatment without troublesome side effects.

References

Sep 21, 2011·The American Journal of Gastroenterology·Sabine RomanPeter J Kahrilas
Mar 5, 2013·Gastroenterology Clinics of North America·Sabine Roman, Peter J Kahrilas
Jan 10, 2014·Case Reports in Gastroenterology·A L PelletierM Merrouche
Aug 6, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Tsutomu NomuraEiji Uchida
Sep 13, 2014·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S MarjouxF Mion
Dec 4, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P J KahrilasUNKNOWN International High Resolution Manometry Working Group
Dec 23, 2014·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Weon Jin KoJoo Young Cho
Aug 28, 2016·Digestive Diseases and Sciences·Mustafa Melih BilgiSerhat Bor

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Citations

Mar 18, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Joan W ChenCharles Cock

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Methods Mentioned

BETA
biopsy

Related Concepts

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Barrett Esophagus

Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.

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