Deaths from asthma in Italy (1974-1988): is there a relationship with changing pharmacological approaches?
In this article we consider the relationship between asthma mortality rates, obtained from the Italian National Institute of Statistics (ISTAT), and the doses of all antiasthmatic drugs except systemic steroids sold in Italy in the years 1974-1988. The total asthma mortality rate showed three different trends: it decreased slowly until 1978 (period A); increased 10-fold from 1979 to 1985, rising from 0.30 to 4.17/100,000 (period B); and remained stable until 1988 (period C). More than half of the deaths in 1988 occurred in people 75 years of age or more. Men died more in the older age groups, while the mortality of women prevailed in the 35- to 54-year age group. In the 5- to 34-year age group the rate rose from 0.01 in 1978 to 0.21 /100,000 in 1986. Coding changes due to the 9th revision of the International Classification of Disease, adopted in Italy in 1979, probably increased the number of deaths being attributed to asthma in case of contemporary mention of bronchitis, a common diagnosis in older men, which showed the greatest increase in mortality. Increased prevalence and awareness of asthma may also have played a role. Although international comparisons strongly suggest undertreatment of asthma in Italy, the doses of ant...Continue Reading
Asthma in the elderly. A comparison between patients with recently acquired and long-standing disease
Mortality trends in a rapidly developing economy in Taiwan. Part I: Comparison with the USA and Japan 1976-1983
Descriptive epidemiology of bronchial reactivity in an adult population: results from a community study
A reappraisal of the United Kingdom epidemic of fatal asthma. Can general mortality data implicate a therapeutic agent?
Is the association between inhaled beta-agonist use and life-threatening asthma because of confounding by severity?
Decrease in asthma mortality rate in Israel from 1991-1995: is it related to increased use of inhaled corticosteroids?
A comparison of the effects of oral prednisone and inhaled beclomethasone dipropionate on circulating leukocytes
Management of endocrine manifestations and the use of mitotane as a chemotherapeutic agent for adrenocortical carcinoma
A neonatal murine model of coxsackievirus A4 infection for evaluation of vaccines and antiviral drugs
Effects of interferons on cortisol production in bovine adrenal fasciculata cells stimulated by adrenocorticotropin
This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.
Allergy and Asthma
Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.