Deaths from total and premature cardiovascular disease associated with high normal blood pressure and hypertension in rural Chinese men and elderly people.

Journal of Human Hypertension
Leilei LiuMing Zhang

Abstract

To investigate the association of blood pressure (BP) categories with total and premature cardiovascular disease (CVD) mortality in rural Chinese. The study included 14,539 adults ≥18 years in rural China. Baseline study visits were conducted in 2007-2008, and follow-up visits in 2013-2014. Data were collected by face-to-face questionnaire interview, and anthropometric and laboratory measurements. A sub-distribution hazards model was used to calculate adjusted sub-distribution hazard ratios (aSHRs) and 95% confidence intervals (CIs). During the 6-year follow-up, 257 total and 209 premature CVD deaths occurred. As compared with normal BP (systolic BP/diastolic BP (SBP/DBP) < 120/80 mmHg), for men and people aged ≥60 years, hypertension (SBP/DBP ≥ 140/90 mmHg) associated with total CVD mortality (aSHR 3.57, 95% CI 2.06-6.17; aSHR 2.15, 1.29-3.56) and premature CVD mortality (aSHR 4.41, 2.37-8.21; aSHR 2.31, 1.27-4.19). Also, as compared with normal BP, for men and people aged ≥60 years with high normal BP (SBP/DBP 120-139/80-89 mmHg), risk of total CVD mortality increased (aSHR 1.85, 1.05-3.28; aSHR 1.78, 1.05-3.04), as was premature CVD mortality (aSHR 1.89, 0.99-3.64; aSHR 1.91, 1.03-3.54). Among men and people aged ≥60 years i...Continue Reading

References

Nov 1, 1993·Circulation·D PerloffB Z Morgenstern
Dec 22, 2000·Clinical Biochemistry·E BairaktariO Tsolas
Aug 6, 2003·Medicine and Science in Sports and Exercise·Cora L CraigPekka Oja
Feb 16, 2006·JAMA : the Journal of the American Medical Association·Dongfeng GuPaul K Whelton
Sep 19, 2007·The Journal of Experimental Medicine·Tomasz J GuzikDavid G Harrison
Oct 24, 2007·Hypertension·Vlado PerkovicStephen MacMahon
Feb 18, 2014·Atherosclerosis·Charalambos VlachopoulosChristodoulos Stefanadis
Apr 3, 2015·Lancet·Neil R PoulterMark Caulfield
Mar 15, 2016·JAMA Internal Medicine·Sarah LewingtonUNKNOWN China Kadoorie Biobank Consortium
May 21, 2017·The Journal of Thoracic and Cardiovascular Surgery·Marianne HuebnerMartin Schumacher
Apr 11, 2018·Diabetes/metabolism Research and Reviews·Yongcheng RenDongsheng Hu
Apr 11, 2018·Journal of the American Heart Association·Mohammad TalaeiWoon-Puay Koh
Mar 24, 2020·Journal of the American College of Cardiology·Lakshmi NambiarHarold L Dauerman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.