Deciphering diversity in populations of various linguistic and ethnic affiliations of different geographical regions of India: analysis based on 15 microsatellite markers

Journal of Genetics
V K KashyapR Trivedi

Abstract

The extent of genetic polymorphism at fifteen autosomal microsatellite markers in 54 ethnically, linguistically and geographically diverse human populations of India was studied to decipher intrapopulation diversity. The parameters used to quantify intrapopulation diversity were average allele diversity, average heterozygosity, allele range (base pairs), and number of alleles. Multilocus genotype frequencies calculated for selected populations were utilized for testing conformity with the assumption of Hardy-Weinberg equilibrium. The exact test values, after Bonferroni correction, showed significant deviation amongst Gowda (vWA, Penta E); Dhangar, Satnami and Gounder (D8S1179); Hmar (FGA); Kuki and Balti (vWA) groups. Relatively low number of alleles and allelic diversity (base-pairs size) had been observed in populations of central India as compared with southern and northern regions of the country. The communities of Indo-Caucasoid ethnic origin and Indo-European linguistic family (Kshatriya of Uttar Pradesh) showed highest allelic diversity, as well as rare alleles, not reported in any other Indian populations. Analysis based on average heterozygosity was also found to be lowest among the populations of central India (0.729)...Continue Reading

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May 12, 2001·Forensic Science International : Synergy·R Dutta, V K Kashyap
Aug 14, 2002·Forensic Science International : Synergy·R TrivediV K Kashyap
Aug 15, 2002·Forensic Science International : Synergy·Christopher M Triggs, John S Buckleton
Oct 17, 2002·Forensic Science International : Synergy·S Gaikwad, V K Kashyap
Nov 13, 2002·Forensic Science International : Synergy·R Ashma, V K Kashyap
Dec 13, 2002·Forensic Science International : Synergy·Sanghamitra Sahoo, V K Kashyap

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Citations

May 12, 2010·Forensic Science International. Genetics·Tania GhoshGanga Nath Jha
Sep 11, 2009·American Journal of Human Biology : the Official Journal of the Human Biology Council·B Mohan ReddyNirmala Alla
Jun 17, 2014·Annals of Human Biology·Sarabjit S Mastana
Oct 12, 2005·Malaria Journal·Sonali GaikwadV K Kashyap
Nov 4, 2005·Annals of Human Genetics·W S WatkinsL B Jorde

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