Deciphering Genomic Regions for High Grain Iron and Zinc Content Using Association Mapping in Pearl Millet

Frontiers in Plant Science
N AnuradhaRakesh K Srivastava

Abstract

Micronutrient malnutrition, especially deficiency of two mineral elements, iron [Fe] and zinc [Zn] in the developing world needs urgent attention. Pearl millet is one of the best crops with many nutritional properties and is accessible to the poor. We report findings of the first attempt to mine favorable alleles for grain iron and zinc content through association mapping in pearl millet. An association mapping panel of 130 diverse lines was evaluated at Delhi, Jodhpur and Dharwad, representing all the three pearl millet growing agro-climatic zones of India, during 2014 and 2015. Wide range of variation was observed for grain iron (32.3-111.9 ppm) and zinc (26.6-73.7 ppm) content. Genotyping with 114 representative polymorphic SSRs revealed 0.35 mean gene diversity. STRUCTURE analysis revealed presence of three sub-populations which was further supported by Neighbor-Joining method of clustering and principal coordinate analysis (PCoA). Marker-trait associations (MTAs) were analyzed with 267 markers (250 SSRs and 17 genic markers) in both general linear model (GLM) and mixed linear model (MLM), however, MTAs resulting from MLM were considered for more robustness of the associations. After appropriate Bonferroni correction, Xpsmp...Continue Reading

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Citations

Jan 13, 2018·Frontiers in Plant Science·Sushil KumarRakesh K Srivastava
Dec 27, 2018·International Journal of Molecular Sciences·Dalia Z AlomariMarion S Röder
Jul 2, 2020·Plants·Rakesh K SrivastavaRajeev Gupta
Mar 20, 2018·Frontiers in Plant Science·A Radhika RamyaRakesh K Srivastava
Nov 30, 2019·Archives of Microbiology·Abhinav AeronRajesh Kumar Meena
Mar 18, 2020·Frontiers in Genetics·Rakesh K SrivastavaRajeev Gupta
Oct 2, 2021·Frontiers in Plant Science·Parminder S VirkWolfgang H Pfeiffer

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Methods Mentioned

BETA
PCA
PCR
genotyping
one hybrid
electrophoresis

Software Mentioned

SAS
ICRISAT
BLAST
SPSS
Primer3Plus
STRUCTURE
TASSEL
AMOVA
DARwin

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