Decision making for diagnosis and management: algorithms from experts for molecular testing

Otolaryngologic Clinics of North America
Jeffrey BumpousBrendan C Stack

Abstract

Cases are presented in light of the current diagnostic and therapeutic trends in management of thyroid nodules and well-differentiated cancers. Demographic, historical, and population-based risk factors are used to risk stratify cases. Ultrasonographic features and other imaging are discussed with regard to appropriateness of utilization and impact on management. The role of traditional cytologic and histopathologic analysis with fine-needle aspiration and intraoperative frozen sections is discussed, including diagnostic nuances and limitations. The emerging role of biomarkers such as Braf are evaluated regarding their role in contemporary assessment of thyroid nodules by reviewing practical cases.

Citations

Jul 31, 2001·International Journal of Cancer. Journal International Du Cancer·C IribarrenG D Friedman
Jul 19, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rishi VashishtaRahul K Shah
Mar 30, 2013·The Journal of Clinical Endocrinology and Metabolism·Nikhil GuptaSteven P Hodak
Aug 28, 2013·The Journal of Clinical Endocrinology and Metabolism·Marina N NikiforovaYuri E Nikiforov

Related Concepts

Recombinant Thyroglobulin
Morbidity Aspects
NRAS gene
N-ras Genes
BRAF protein, human
Nodule
Immunologic Adjuvants
Cytological Techniques
Test, Cytology, Digestive
Adjuvant

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.