PMID: 6991860Jul 1, 1980Paper

Decline of postheparin plasma lipoprotein lipase in acromegalic patients

Metabolism: Clinical and Experimental
T MuraseS Yoshida

Abstract

Lipoprotein lipase and hepatic triglyceride lipase in postheparin plasma were measured in seven patients with active acromegaly by an immunochemical method utilizing antiserum prepared against hepatic triglyceride lipase. A mild or moderate hypertriglyceridemia was shown, with plasma triglyceride concentrations between 156 and 544 mg/dl. Lipoprotein lipase was found to be decreased in all patients (p less than 0.001). Hepatic triglyceride lipase was also low in these patients (p less than 0.001). We speculate that acromegalic hypertriglyceridemia is mediated, at least in part, by the decline in lipoprotein lipase and possibly by the decline in hepatic triglyceride lipase activities.

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Citations

Apr 1, 1989·European Journal of Pediatrics·M OhnoT Murase
Jan 1, 1983·Zeitschrift Für Parasitenkunde·K HiraiY Yamane
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Sep 14, 2021·Current Atherosclerosis Reports·Patricia HernandezDaniel Soffer

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