Declining sperm count and fertility in males: an epidemiological controversy

Archives of Andrology
F ParazziniE Colli

Abstract

There have been several suggestions from different populations that sperm count has decreased in the past 20 years. Concerns have, however, been raised in the interpretation of these findings, particularly with regards to subject selection mechanisms and data-analysis. Furthermore, these findings are inconsistent with the reports that male infertility rates have remained constant during the past 3 decades. The increased number of men seeking consultation on infertility may only be the result of the tendency of couples to delay pregnancy and the increased availability of treatment. Moreover, sperm concentration is not always in itself the determinant of male fertility, so the use of sperm count as an indicator of male infertility in epidemiological studies should be considered with caution.

References

Jul 1, 1978·Alcoholism, Clinical and Experimental Research·G G GordonC S Lieber
Oct 7, 1976·The New England Journal of Medicine·G G GordonC S Lieber
Sep 12, 1992·BMJ : British Medical Journal·E CarlsenN E Skakkebaek
Jul 1, 1989·Journal of Reproduction and Fertility·N B OldereidK Purvis
Oct 1, 1986·Fertility and Sterility·R J StillmanB P Sachs
Aug 1, 1987·Fertility and Sterility·R K DikshitS M Mansuri
Jun 1, 1987·European Journal of Cancer & Clinical Oncology·P BoyleA G Robertson
Jun 1, 1995·International Journal of Andrology·F ParazziniL Fedele
Aug 1, 1995·International Journal of Andrology·R Mieusset, L Bujan
Feb 2, 1995·The New England Journal of Medicine·J AugerP Jouannet
Feb 2, 1995·The New England Journal of Medicine·R J Sherins
Jul 2, 1994·BMJ : British Medical Journal·S Farrow
Jul 2, 1994·BMJ : British Medical Journal·P BromwichA Walker
Sep 1, 1993·Archives of Andrology·F ParazziniL Fedele
Jun 12, 1993·BMJ : British Medical Journal·J Suominen, M Vierula

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Citations

Sep 2, 2005·Nature Reviews. Genetics·Stephen A Krawetz
May 18, 2005·Asian Journal of Andrology·Rui Pires Martins, Stephen A Krawetz

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