Decoding material-specific memory reprocessing during sleep in humans

Nature Communications
M SchönauerS Gais

Abstract

Neuronal learning activity is reactivated during sleep but the dynamics of this reactivation in humans are still poorly understood. Here we use multivariate pattern classification to decode electrical brain activity during sleep and determine what type of images participants had viewed in a preceding learning session. We find significant patterns of learning-related processing during rapid eye movement (REM) and non-REM (NREM) sleep, which are generalizable across subjects. This processing occurs in a cyclic fashion during time windows congruous to critical periods of synaptic plasticity. Its spatial distribution over the scalp and relevant frequencies differ between NREM and REM sleep. Moreover, only the strength of reprocessing in slow-wave sleep influenced later memory performance, speaking for at least two distinct underlying mechanisms between these states. We thus show that memory reprocessing occurs in both NREM and REM sleep in humans and that it pertains to different aspects of the consolidation process.

References

Jul 1, 1995·Behavioural Brain Research·C Smith
Jul 1, 1995·Behavioural Brain Research·A GiudittaS Vescia
Jul 29, 1994·Science·M A Wilson, B L McNaughton
Oct 29, 1993·Science·M SteriadeT J Sejnowski
Oct 19, 1999·Nature·K M O'CravenN Kanwisher
Apr 20, 2000·Journal of Cognitive Neuroscience·R StickgoldJ A Hobson
Jul 21, 2000·Nature Neuroscience·P MaquetA Cleeremans
Jan 18, 2003·Sleep Medicine Reviews·M V. Ambrosini, A Giuditta
Jan 12, 2005·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Meredith Minear, Denise C Park
Feb 3, 2005·Sleep·Manuel SchabusJosef Zeitlhofer
Oct 1, 2005·Science·Marcello MassiminiGiulio Tononi
Dec 2, 2005·Annual Review of Psychology·Matthew P Walker, Robert Stickgold
Jun 3, 2006·Learning & Memory·Steffen GaisJan Born
Aug 11, 2006·Trends in Cognitive Sciences·Kenneth A NormanJames V Haxby
Nov 7, 2006·Nature·Lisa MarshallJan Born
Dec 19, 2006·Nature Neuroscience·Daoyun Ji, Matthew A Wilson
Oct 16, 2007·Sleep Medicine Reviews·Till RoennebergMartha Merrow
Nov 17, 2007·Science·David R EustonBruce L McNaughton
Mar 22, 2008·Current Biology : CB·Claire JacksonGabriel Horn
Jan 27, 2009·Annals of Statistics·Jianqing Fan, Yingying Fan
Jun 2, 2009·Nature Neuroscience·Adrien PeyracheFrancesco P Battaglia
Aug 19, 2009·PLoS Biology·Carien S LansinkCyriel M A Pennartz
Aug 26, 2009·Psychological Bulletin·Matthew P Walker, Els van der Helm
Sep 15, 2009·Nature Neuroscience·Gabrielle GirardeauMichaël B Zugaro
Oct 13, 2009·Nature Neuroscience·Jan ScholzHeidi Johansen-Berg
Dec 8, 2009·Science·John D RudoyKen A Paller
Apr 13, 2011·Neuron·Ronald L Davis
May 4, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Anthony P Atkinson, Ralph Adolphs
May 6, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Cristina MarzanoLuigi De Gennaro
Mar 28, 2012·Proceedings of the National Academy of Sciences of the United States of America·Mélanie BolyHabib Benali
Sep 25, 2012·Neuron·Andres D GrosmarkGyörgy Buzsáki
Oct 23, 2012·Current Opinion in Neurobiology·Josh Dubnau, Ann-Shyn Chiang
Mar 26, 2013·Neuron·John E Lisman, Ole Jensen
Apr 6, 2013·Science·T HorikawaY Kamitani
Apr 17, 2013·Physiological Reviews·Björn Rasch, Jan Born
Aug 30, 2013·Journal of Cognitive Neuroscience·Monika SchönauerSteffen Gais
Sep 14, 2013·Current Biology : CB·Ted AbelMatthew P Walker
Nov 12, 2013·Trends in Neurosciences·Lisa GenzelFrancesco P Battaglia

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Citations

May 16, 2018·Annals of the New York Academy of Sciences·Nicola Cellini, Alessandra Capuozzo
Apr 14, 2018·Neural Computation·Shizhao LiuZhe Chen
Oct 12, 2019·Psychological Science·Kristin E G SandersMark Beeman
Apr 7, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Arnaud Boutin, Julien Doyon
Apr 7, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Thomas Schreiner, Tobias Staudigl
Aug 28, 2019·Nature Neuroscience·Jens G KlinzingJan Born
Dec 24, 2019·Journal of Sleep Research·Kathrin BotheJuergen Birklbauer
Aug 17, 2018·Sleep·Svenja BrodtMonika Schönauer
Apr 21, 2020·Journal of Sleep Research·Dorothee PöhlchenMonika Schönauer
Dec 16, 2018·Scientific Reports·Roy CoxRobert Stickgold
Dec 19, 2018·ELife·Björn Rasch
Jul 28, 2020·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Svenja Brodt, Steffen Gais
May 3, 2018·Scientific Reports·Michael Craig, Michaela Dewar
Oct 12, 2018·Scientific Reports·Elizabeth A McDevittSara C Mednick
Jun 2, 2020·Frontiers in Neuroscience·Jean-Baptiste EichenlaubSydney S Cash
Sep 19, 2020·Annual Review of Psychology·Ken A PallerEitan Schechtman
Jul 3, 2019·Trends in Immunology·Tanja LangeJürgen Westermann
Feb 16, 2021·Sleep Medicine Reviews·Kevin J MacDonald, Kimberly A Cote
May 21, 2021·Neurobiology of Learning and Memory·Claudia Picard-DelandTore Nielsen
May 27, 2021·Nature Communications·Thomas SchreinerBernhard P Staresina
Jul 31, 2021·Psychonomic Bulletin & Review·Emily T CowanVishnu P Murty

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Software Mentioned

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