Decoding semi-constrained brain activity from FMRI using support vector machines and gaussian processes.

PloS One
Jessica SchrouffChristophe Phillips

Abstract

Predicting a particular cognitive state from a specific pattern of fMRI voxel values is still a methodological challenge. Decoding brain activity is usually performed in highly controlled experimental paradigms characterized by a series of distinct states induced by a temporally constrained experimental design. In more realistic conditions, the number, sequence and duration of mental states are unpredictably generated by the individual, resulting in complex and imbalanced fMRI data sets. This study tests the classification of brain activity, acquired on 16 volunteers using fMRI, during mental imagery, a condition in which the number and duration of mental events were not externally imposed but self-generated. To deal with these issues, two classification techniques were considered (Support Vector Machines, SVM, and Gaussian Processes, GP), as well as different feature extraction methods (General Linear Model, GLM and SVM). These techniques were combined in order to identify the procedures leading to the highest accuracy measures. Our results showed that 12 data sets out of 16 could be significantly modeled by either SVM or GP. Model accuracies tended to be related to the degree of imbalance between classes and to task performan...Continue Reading

References

Dec 1, 1988·Journal of Consulting and Clinical Psychology·A T BeckR A Steer
Dec 18, 2001·Human Brain Mapping·Thomas E Nichols, Andrew P Holmes
Apr 24, 2002·NeuroImage·Chloe HuttonRobert Turner
Jun 14, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C ViolaniL Ferini Strambi
Apr 27, 2005·Nature Neuroscience·John-Dylan Haynes, Geraint Rees
Apr 27, 2005·Nature Neuroscience·Yukiyasu Kamitani, Frank Tong
Dec 24, 2005·Science·Sean M PolynKenneth A Norman
Jun 23, 2006·Nature Reviews. Neuroscience·John-Dylan Haynes, Geraint Rees
Aug 11, 2006·Trends in Cognitive Sciences·Kenneth A NormanJames V Haxby
Feb 13, 2007·Current Biology : CB·John-Dylan HaynesRichard E Passingham
Jan 19, 2008·Brain : a Journal of Neurology·Stefan KlöppelRichard S J Frackowiak
Mar 17, 2009·Current Biology : CB·Demis HassabisEleanor A Maguire
Mar 17, 2010·Current Biology : CB·Martin J ChadwickEleanor A Maguire

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Citations

Feb 19, 2013·Neuroinformatics·J SchrouffJ Mourão-Miranda
Apr 5, 2016·Australasian Physical & Engineering Sciences in Medicine·Rana Fayyaz AhmadJafri Malin Abdullah
May 21, 2013·NeuroImage·O M DoyleA F Marquand
Feb 13, 2014·Brain Imaging and Behavior·Mahdi RamezaniIngrid Johnsrude
Sep 23, 2016·Computational Intelligence and Neuroscience·Danilo DonGiovanni, Lucia Maria Vaina
Apr 8, 2017·Journal of Cognitive Neuroscience·Angie A KehagiaTrevor W Robbins
Oct 7, 2017·Journal of Cognitive Neuroscience·Steve MajerusChristophe Phillips
Jan 4, 2018·Neuroinformatics·Jessica SchrouffJ Mourão-Miranda
Mar 7, 2017·Frontiers in Neuroscience·Luca BaldassarreJanaina Mourão-Miranda
Dec 10, 2019·Cerebral Cortex·Benjamin KowialiewskiSteve Majerus
Aug 12, 2021·Cerebral Cortex·Lucie AttoutSteve Majerus

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Methods Mentioned

BETA
feature extraction
features extraction

Software Mentioned

LIBSVM
SVM
FieldMap

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