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Decoding the genome: a modified view

Nucleic Acids Research

Jan 13, 2004

Paul F Agris

Abstract

Transfer RNA's role in decoding the genome is critical to the accuracy and efficiency of protein synthesis. Though modified nucleosides were identified in RNA 50 years ago, only recently has their importance to tRNA's ability to decode cognate and wobble codons become apparent. RNA modi...read more

Mentioned in this Paper

Thermodynamics
Asparagine
Abnormal Degeneration
Genome
Valine
Post-Translational Protein Processing
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
Transfer RNA
Protein Biosynthesis
Paper Details
References
  • References144
  • Citations183
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  • References144
  • Citations183
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Decoding the genome: a modified view

Nucleic Acids Research

Jan 13, 2004

Paul F Agris

PMID: 14715921

DOI: 10.1093/nar/gkh185

Abstract

Transfer RNA's role in decoding the genome is critical to the accuracy and efficiency of protein synthesis. Though modified nucleosides were identified in RNA 50 years ago, only recently has their importance to tRNA's ability to decode cognate and wobble codons become apparent. RNA modi...read more

Mentioned in this Paper

Thermodynamics
Asparagine
Abnormal Degeneration
Genome
Valine
Post-Translational Protein Processing
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
Transfer RNA
Protein Biosynthesis

Similar Papers Found In These Feeds

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

Chromosomal Translocation

Chromosomal Translocation occur when regions on two chromosomes breaks and swaps places or when a region is attached to another chromosome. Discover the latest research on Chromosomal Translocation here.

Related Papers

Nature Structural & Molecular Biology

The role of modifications in codon discrimination by tRNA(Lys)UUU

Nature Structural & Molecular BiologyNovember 24, 2004
Frank V MurphyPaul F Agris
Paper Details
References
  • References144
  • Citations183
12345...
  • References144
  • Citations183
12345...
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