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Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species

Cell Systems

May 22, 2019

Genevieve L. Stein-O'BrienElana J. Fertig

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Abstract

Analysis of gene expression in single cells allows for decomposition of cellular states as low-dimensional latent spaces. However, the interpretation and validation of these spaces remains a challenge. Here, we present scCoGAPS, which defines latent spaces from a source single-cell RNA-...read more

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Cervical Atlas
Brain
Chromatin
Gene Expression
Laboratory mice
Retina
Retinal Diseases
Psychological Transfer
Internal
Anatomical Space Structure
177
6
90
1
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Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species

Cell Systems

May 22, 2019

Genevieve L. Stein-O'BrienElana J. Fertig

PMID: 31121116

DOI: 10.1016/j.cels.2019.04.004

Abstract

Analysis of gene expression in single cells allows for decomposition of cellular states as low-dimensional latent spaces. However, the interpretation and validation of these spaces remains a challenge. Here, we present scCoGAPS, which defines latent spaces from a source single-cell RNA-...read more

Mentioned in this Paper

Cervical Atlas
Brain
Chromatin
Gene Expression
Laboratory mice
177
6
90
1
Paper Details
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