Decomposition of drug mixture in Fenton and photo-Fenton processes: comparison to singly treatment, evolution of inorganic ions and toxicity assay

Chemosphere
Ardhendu Sekhar Giri, Animes Kumar Golder

Abstract

The degradation of three pharmaceutical compounds i.e. chloramphenicol (CHPL), ciprofloxacin (CIP) and dipyrone (DIPY) singly and from equimolar (CCD) mixture has been investigated in Fenton and photo-Fenton processes. Drug mineralization was slightly less when present singly than their mixture. The degradation efficiency was likely hindered due to formation of common ions like Cl(-), F(-), NH4(+) and NO3(-). Addition of the same ions i.e. Cl(-) and F(-) in drug solution released upon cleavage of CHPL and CIP in CCD mixture suppressed the decomposition efficiency remarkably in both the oxidation processes. The major intermediates appeared in the mass spectra in combination of ion chromatograph were used to validate the routes of CCD decomposition and evolution inorganic ions. Furthermore, the bacterial toxicity assay was investigated using Escherichia coli (E. coli). The average reduction in cell death was about 38% in CCD system compared to 52%, 42% and 47% for CHPL, CIP and DIPY, respectively.

References

Apr 1, 1984·Journal of Clinical Pharmacology·W G KramerL K Pickering
Feb 24, 1999·The Science of the Total Environment·M StumpfW Baumann
May 13, 2004·Journal of Pharmaceutical and Biomedical Analysis·Hakan ErgünJacob V Aranda
Aug 6, 2004·Chemosphere·S WiegelA Wanke
Mar 3, 2006·Environmental Science & Technology·George P AnipsitakisMichael A Gonzalez
May 2, 2006·Environmental Science & Technology·Francesco PomatiDavide Calamari
Aug 21, 2007·Journal of Hazardous Materials·D G Joakim LarssonNicklas Paxeus
Apr 24, 2013·Environmental Science & Technology·Bin LiangDuu-Jong Lee
May 7, 2013·Environmental Science & Technology·Clément LevardGordon E Brown

❮ Previous
Next ❯

Citations

Dec 5, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleksandra PieczyńskaEwa M Siedlecka
Jul 26, 2017·Environmental Monitoring and Assessment·Maryam SalimiHamid Reza Sobhi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.