PMID: 11900500Mar 20, 2002Paper

Deconstructing the placebo effect and finding the meaning response

Annals of Internal Medicine
Daniel E Moerman, Wayne B Jonas

Abstract

We provide a new perspective with which to understand what for a half century has been known as the "placebo effect." We argue that, as currently used, the concept includes much that has nothing to do with placebos, confusing the most interesting and important aspects of the phenomenon. We propose a new way to understand those aspects of medical care, plus a broad range of additional human experiences, by focusing on the idea of "meaning," to which people, when they are sick, often respond. We review several of the many areas in medicine in which meaning affects illness or healing and introduce the idea of the "meaning response." We suggest that use of this formulation, rather than the fixation on inert placebos, will probably lead to far greater insight into how treatment works and perhaps to real improvements in human well-being.

Citations

Apr 26, 2008·Der Anaesthesist·J Oeltjenbruns, M Schäfer
Jul 22, 2006·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·K Linde
Sep 7, 2004·Lasers in Medical Science·Peter Whittaker
Oct 15, 2005·Health Care Analysis : HCA : Journal of Health Philosophy and Policy·Colin Cheyne
Oct 3, 2009·Health Care Analysis : HCA : Journal of Health Philosophy and Policy·Hannah BradbyMary Robson
May 15, 2012·Journal of Behavioral Medicine·Ben Whalley, Michael E Hyland
Apr 13, 2011·The Journal of Medical Humanities·Stephen Loftus
Aug 23, 2012·The Journal of Medical Humanities·Brian McKenna
Jul 15, 2009·Culture, Medicine and Psychiatry·Ted J KaptchukEric E Jacobson
Nov 13, 2007·Journal of General Internal Medicine·Rachel Sherman, John Hickner
Apr 18, 2007·Current Allergy and Asthma Reports·Ron Eccles
Sep 14, 2002·Current Gastroenterology Reports·George F Longstreth, Douglas A Drossman
Sep 30, 2010·Current Psychiatry Reports·Richard L Kradin
Feb 28, 2004·Science and Engineering Ethics·Franklin G Miller
Jun 12, 2012·Journal of Acupuncture and Meridian Studies·Fabrizio Benedetti
Nov 14, 2002·Urology·C A Buffington
Mar 15, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Marshall PitzCharles N Bernstein
Sep 16, 2005·Journal of Personality and Social Psychology·Andrew L GeersSuzanne G Helfer
Jul 6, 2011·Nature Reviews. Urology·Altaf MangeraMelanie Plested
Mar 20, 2013·The New England Journal of Medicine·Rachelle Buchbinder
Aug 7, 2009·The New England Journal of Medicine·Rachelle BuchbinderBridie Murphy
Jul 12, 2002·The New England Journal of Medicine·Sam Horng, Franklin G Miller
Aug 10, 2007·The American Journal of Clinical Hypnosis·Amir Raz
Aug 10, 2007·The American Journal of Clinical Hypnosis·Edward J Frischholz
Aug 20, 2010·Anthropology & Medicine·Jeffrey Longhofer, Jerry Floersch
Feb 2, 2012·Anthropology & Medicine·Ann M Ostenfeld-Rosenthal
Dec 10, 2009·The American Journal of Bioethics : AJOB·Daniel E Moerman
Dec 10, 2009·The American Journal of Bioethics : AJOB·Carlo Petrini
Apr 5, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Iris R BellGary E Schwartz
Jan 23, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Bruce BarrettDavid Rabago
Jul 16, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Sarah BrienGeorge T Lewith
Jul 16, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Stephen Birch
Mar 8, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Elizabeth A ThompsonDavid Reilly
Nov 22, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Jennifer JacobsDavid Katz
May 2, 2006·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Stephen Birch
Jan 18, 2008·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·David P RakelEmily Ferrara
Nov 8, 2008·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Andrew F Long
Jan 7, 2009·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Maria B OspinaDavid Shannahoff-Khalsa
Aug 22, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Benjamin KliglerAlison Karasz
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Tao Liu
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Elizabeth H Logue
Jul 26, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Tao Liu, Cui-Ping Yu
Oct 6, 2006·Current Opinion in Anaesthesiology·Fabrizio BenedettiAntonella Pollo
Sep 22, 2012·Journal of Psychiatric Practice·Mary V Seeman, Neil Seeman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved