Decontamination of human and rabbit skin experimentally contaminated with 99mTc radionuclide using the active components of "Shudhika"-a skin decontamination kit

Prehospital and Disaster Medicine
S RanaRakesh Kumar Sharma

Abstract

Radioactive contamination can occur as a result of accidental or intentional release of radioactive materials (RM) into the environment. RM may deposit on clothing, skin, or hair. Decontamination of contaminated persons should be done as soon as possible to minimize the deleterious health effects of radiation. The goal of this study was to evaluate the decontamination efficiency (for residual contaminant) of the active components of "Shudhika," an indigenously developed skin decontamination kit. The study kit is for external radioactive decontamination of intact skin. Decontamination efficiency was evaluated on the skin surface of rabbit (n = 6) and human volunteers (n = 13). 99mTc sodium pertechnetate (200-250 μCi) was used as the radio-contaminant. Skin surface area (5 × 5 cm2) of thoracic abdominal region of the rabbit and the forearm and the palm of human volunteers were used for the study. Decontamination was performed by using cotton swabs soaked with chemical decontamination agents of the kit. Decontamination efficiency (% of the contaminant removed) was calculated for each component of the study. Overall effectiveness of the kit was calculated to be 85% ± 5% in animal and 92% ± 3% in human skin surfaces. Running water a...Continue Reading

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Citations

Apr 2, 2014·Disaster Medicine and Public Health Preparedness·Sudha RanaRakesh Kumar Sharma
May 30, 2021·Chemico-biological Interactions·Greta Camilla MagnanoFrancesca Larese Filon

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