Decrease in fat oxidation following a meal in weight-reduced individuals: a possible mechanism for weight recidivism

Metabolism: Clinical and Experimental
D L BallorJ Calles-Escandon

Abstract

This study examined the effect that dietary-induced weight loss has on body composition, energy metabolism, and substrate oxidation at rest and during the 5-hour period following a meal. Twenty older (age:mean +/- SE, 61 +/- 1 years; range, 56 to 70 y) obese (body mass index > 32 kg/m2) subjects (12 women, eight men) completed an 11-week dietary restriction program in which they lost 9 +/- l kg. Fat and fat-free mass were reduced (P < .05) by 15% and 5%, respectively. Resting metabolic rate decreased by 15% (P < .05). Overall, weight loss did not alter the percentage of energy derived from fat sources (approximately 47% of energy) under resting conditions. In contrast, the percentage of calories derived from fat during the 5-hour postmeal period decreased from baseline to post-weight loss from 38% +/- 3% to 26% +/- 4% (P < .05) of total calories expended. The reduction in fat oxidation subsequent to a meal may facilitate fat storage, and may be one mechanism by which one regains weight following weight loss.

References


❮ Previous
Next ❯

Citations

Apr 7, 2000·Molecular Aspects of Medicine·J MercierR Ventura
Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A Pérez-MartinJ Mercier
Jul 10, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Paul S MacLeanJames O Hill
Jun 17, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Paul S MacleanMatthew R Jackman
Feb 1, 1997·Aging : Clinical and Experimental Research·J Calles-Escandón, E T Poehlman
Sep 19, 2009·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A Schwartz, E Doucet
Aug 6, 2013·Physiology & Behavior·Christopher N OchnerF Xavier Pi-Sunyer
Nov 7, 2012·Clinical Science·Priya Sumithran, Joseph Proietto
Jun 29, 2006·American Journal of Physiology. Endocrinology and Metabolism·Matthew R JackmanDaniel H Bessesen
Feb 22, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Matthew R JackmanPaul S MacLean
Oct 29, 2000·American Journal of Physiology. Endocrinology and Metabolism·J Y KimJ A Houmard
Feb 22, 2001·Journal of Applied Physiology·N R GuesbeckJ A Houmard
Jan 19, 2019·Sports·Jackson James PeosPaul Fournier
Feb 5, 2009·Biological Research for Nursing·Mary Madeline Rogge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.