Decrease of capsular opacification with adjunctive mitomycin C in combined glaucoma and cataract surgery

Ophthalmology
D H ShinS B Muenk

Abstract

The authors investigated the incidence of capsular opacification requiring YAG capsulotomy after primary trabeculectomy combined with phacoemulsification and implantation of all polymethylmethacrylate intraocular lenses. A prospective randomized study. One hundred seventy-four eyes of 174 nonselected patients with primary open-angle glaucoma (POAG) were randomized to either no adjunctive mitomycin C (MMC) control group of 93 eyes of 93 patients) or adjunctive subconjunctival MMC (MMC group of 81 eyes of 81 patients) during the primary glaucoma triple procedure (PGTP). Primary glaucoma triple procedure with and without MMC and YAG laser capsulotomy for posterior capsular opacification (PCO) was performed. The incidences of YAG capsulotomy for PCO were compared between the control and MMC groups and also between the control group and the MMC subgroups (1 minute, 3 minutes, and 5 minutes of MMC application) using Kaplan-Meier analysis with Mantel-Cox log-rank test. Cox proportional hazard regression analysis also was performed to identify significant factors affecting capsular opacification. The control and MMC groups were similar in preoperative characteristics. However, the probability of PCO requiring YAG capsulotomy was signif...Continue Reading

References

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Citations

May 13, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·G U AuffarthA J Reuland
Dec 16, 2000·Documenta Ophthalmologica. Advances in Ophthalmology·H J BeckersC A Webers
Oct 18, 2000·Journal of Cataract and Refractive Surgery·H S ChungH B Kim
Dec 28, 1999·Journal of Cataract and Refractive Surgery·M R Tetz, C Nimsgern
Aug 8, 2001·Journal of Cataract and Refractive Surgery· Inan UUC Güler
Mar 20, 2004·Journal of Cataract and Refractive Surgery·Anna ZaczekCharlotta Zetterström
Dec 25, 2004·Journal of Cataract and Refractive Surgery·Viviana FernandezJean-Marie Parel
Oct 18, 2000·Journal of Cataract and Refractive Surgery·S A Obstbaum
Dec 31, 2009·Current Opinion in Ophthalmology·Joshua C Teichman, Iqbal Ike K Ahmed
Oct 20, 2012·Current Opinion in Ophthalmology·Yu-Chi LiuJodhbir S Mehta
Jul 30, 2014·The Cochrane Database of Systematic Reviews·Roger E ThomasBennett C Thomas
Jan 10, 2001·Current Opinion in Ophthalmology·E Bertelmann, C Kojetinsky

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