Decreased activity of daily living produced by the combination of Alzheimer's disease and lower limb fracture in elderly requiring nursing care.

Environmental Health and Preventive Medicine
Toshimitsu InagawaHiroyuki Nakamura

Abstract

Alzheimer's disease (AD) impairs cognitive functions, subsequently decreasing activity of daily living (ADL), and is frequently accompanied by lower limb fracture including hip fracture in the elderly. However, there have been few studies on what kinds of physical functions are affected or what degrees of dysfunction are produced by this combination. This study aims to clarify the relationship between decreased ADL and the combination of AD and lower limb fracture. We examined present illness and ADL in 4340 elderly aged 82.8 ± 9.36 years [average ± standard deviation (SD)] requiring nursing care and compared ADL between elderly with and without AD or lower limb fracture treated with surgery or conservatively using analysis of covariance (ANCOVA), with age and sex as covariants. We recognized that activities of cognitive function (p < 0.001), eating (dysphagia) (p < 0.001), eating (feeding) (p < 0.001), and toilet use (p < 0.001) in the elderly with AD were significantly lower than in those without the disease, even after adjusting for sex and age. Activities of bed mobility (p < 0.05), transfer and locomotion (p < 0.001), and bathing (p < 0.05) in the elderly with a fracture treated with surgery were significantly lower, which...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Aug 20, 2003·Archives of Neurology·Liesi E HebertDenis A Evans
May 10, 2005·Scandinavian Journal of Caring Sciences·Birgitta OlofssonYngve Gustafson
Jul 30, 2005·Health and Quality of Life Outcomes·Jiro OkochiTai Takahashi
Nov 1, 2005·Archives of Gerontology and Geriatrics·Lainie V MoncadaColleen Christmas
Mar 8, 2007·Journal of the American Geriatrics Society·Joan D PenrodAlbert L Siu
Sep 14, 2007·Journal of Alzheimer's Disease : JAD·Elena MarianiPatrizia Mecocci
Apr 22, 2008·Journal of the American Geriatrics Society·Jane L GivensEdward R Marcantonio
Dec 24, 2008·Journal of Orthopaedic Trauma·Wilhelmina EkströmJan Tidermark
May 29, 2009·Alzheimer Disease and Associated Disorders·Mee Kyung SuhDuk L Na
Oct 14, 2009·BMC Health Services Research·Katrine A NielsenReimar W Thomsen
Mar 12, 2010·Alzheimer Disease and Associated Disorders·Virginia Mazoteras MuñozBruno Vellas
Jun 4, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T AlarcónA Otero
Dec 29, 2010·Journal of Alzheimer's Disease : JAD·Rui ZhouYan-Jiang Wang
Jan 19, 2011·Arquivos de neuro-psiquiatria·Sheilla de Medeiros CorreiaLeticia Lessa Mansur
Feb 10, 2011·Nature Reviews. Neurology·Christiane ReitzRichard Mayeux

❮ Previous
Next ❯

Citations

May 19, 2018·International Journal of Environmental Research and Public Health·Nurul Izzah IbrahimAhmad Nazrun Shuid
Dec 17, 2016·European Review of Aging and Physical Activity : Official Journal of the European Group for Research Into Elderly and Physical Activity·Alexander BarthGabriele Doblhammer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.