Decreased centrality of cortical volume covariance networks in autism spectrum disorders

Journal of Psychiatric Research
Joana Bisol BalardinJoão Ricardo Sato

Abstract

Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by atypical structural and functional brain connectivity. Complex network analysis has been mainly used to describe altered network-level organization for functional systems and white matter tracts in ASD. However, atypical functional and structural connectivity are likely to be also linked to abnormal development of the correlated structure of cortical gray matter. Such covariations of gray matter are particularly well suited to the investigation of the complex cortical pathology of ASD, which is not confined to isolated brain regions but instead acts at the systems level. In this study, we examined network centrality properties of gray matter networks in adults with ASD (n = 84) and neurotypical controls (n = 84) using graph theoretical analysis. We derived a structural covariance network for each group using interregional correlation matrices of cortical volumes extracted from a surface-based parcellation scheme containing 68 cortical regions. Differences between groups in closeness network centrality measures were evaluated using permutation testing. We identified several brain regions in the medial frontal, parietal and temporo-occip...Continue Reading

References

Jul 2, 1998·Brain : a Journal of Neurology·M M Mesulam
Sep 14, 2000·Proceedings of the National Academy of Sciences of the United States of America·B Fischl, A M Dale
Jul 24, 2002·Brain : a Journal of Neurology·Fulvia CastelliUta Frith
Jan 23, 2004·Nature·Bogdan DraganskiArne May
Jun 26, 2004·Annual Review of Neuroscience·Giacomo Rizzolatti, Laila Craighero
Oct 22, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew K BelmonteSara J Webb
Apr 30, 2005·Biological Psychiatry·David E WelchewEd Bullmore
Sep 9, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Andrea MechelliCathy J Price
Jan 10, 2006·Brain : a Journal of Neurology·Andrea E Cavanna, Michael R Trimble
Feb 2, 2006·Journal of Autism and Developmental Disorders·Francesca Happé, Uta Frith
Jul 25, 2006·Progress in Neuro-psychopharmacology & Biological Psychiatry·Murad AtmacaA Kursad Poyraz
Feb 6, 2007·Current Opinion in Neurobiology·Daniel H Geschwind, Pat Levitt
Oct 26, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christine Wu NordahlDavid C Van Essen
Feb 1, 2008·Brain : a Journal of Neurology·Natalia M KleinhansElizabeth Aylward
Apr 17, 2008·Nature Reviews. Genetics·Brett S Abrahams, Daniel H Geschwind
Jul 4, 2008·PLoS Biology·Patric HagmannOlaf Sporns
Sep 12, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Danielle S BassettAndreas Meyer-Lindenberg
Feb 5, 2009·Nature Reviews. Neuroscience·Ed Bullmore, Olaf Sporns
Apr 21, 2009·Neuron·William W SeeleyMichael D Greicius
Oct 13, 2009·NeuroImage·Mikail Rubinov, Olaf Sporns
Apr 14, 2010·Archives of Neurology·Brett S Abrahams, Daniel H Geschwind
Apr 30, 2010·Frontiers in Neuroinformatics·Gorka Zamora-LópezJürgen Kurths
Jul 14, 2010·Autism Research : Official Journal of the International Society for Autism Research·Oswald J N BloemenDeclan G M Murphy
Oct 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Brandon A ZielinskiWilliam W Seeley
Oct 15, 2010·Cerebral Cortex·Jeffrey S AndersonJanet E Lainhart
Oct 27, 2010·Neuroscience and Biobehavioral Reviews·Rajesh K KanaBrittany G Travers
Oct 5, 2011·Cerebral Cortex·Xi-Nian ZuoMichael P Milham
Feb 23, 2012·Neuroscience and Biobehavioral Reviews·Marcel Adam JustSashank Varma
Jul 18, 2012·Molecular Psychiatry·C EckerD G M Murphy
Aug 7, 2012·Autism Research : Official Journal of the International Society for Autism Research·Jane McGrathHugh Garavan
Nov 28, 2012·PloS One·Brandon A ZielinskiJanet E Lainhart
Dec 25, 2012·Journal of Psychiatric Research·João Ricardo SatoChristine Ecker
Feb 15, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Aaron Alexander-BlochJay Giedd
Mar 28, 2013·Nature Reviews. Neuroscience·Aaron Alexander-BlochEd Bullmore
May 29, 2013·NeuroImage·Alan C Evans

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Citations

Dec 13, 2017·Frontiers in Neurology·Garrett J CardonDonald C Rojas
Jun 22, 2017·Cerebral Cortex·R A I BethlehemS Baron-Cohen
Jan 29, 2019·Frontiers in Neuroscience·Amirali Kazeminejad, Roberto C Sotero
Jun 30, 2019·Frontiers in Neuroscience·Farzad V FarahaniNichole R Lighthall
Dec 22, 2020·Frontiers in Psychiatry·Ábel FóthiAndrás Lőrincz

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