Decreased cortical and subcortical response to inhibition control after sleep deprivation

Brain Imaging and Behavior
Rui ZhaoWei Qin

Abstract

The effects of sleep deprivation (SD) on the neural substrates of inhibition control are poorly understood. Here we used functional magnetic resonance imaging to examine the effects of 24 h of SD on cerebral activation during a stop-signal task in 20 normal young subjects. Behaviorally, subjects showed significantly delayed stop-signal reaction time (SSRT) following SD. In addition, reduced cerebral activation was found in the "stopping network" (including the inferior frontal gyrus [IFG], supplementary motor area, subthalamic nucleus [STN] and insula) and vision-related regions (occipital cortex, lingual gyrus and fusiform gyrus) after SD. These findings support the hypothesis that task-related activation in prefrontal cortex is particularly vulnerable to SD. After rested wakefulness (RW), significant negative correlations were found between SSRT and cerebral activation in left IFG, right hippocampus, right lingual gyrus, left STN and bilateral fusiform gyrus, with activation in left IFG making the most contribution. After SD, significant negative correlations were found between SSRT and activation in right middle frontal cortex, right IFG and left lingual gyrus, with the activation in right IFG making the most contribution. F...Continue Reading

References

May 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·J BogousslavskyF Regli
Mar 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·J A Horne
Mar 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·D A GusnardM E Raichle
Jan 11, 2003·Acta Psychologica·Guido P H BandGordon D Logan
Jan 22, 2003·Nature Neuroscience·Adam R AronTrevor W Robbins
Mar 31, 2004·Trends in Cognitive Sciences·Adam R AronRussell A Poldrack
Apr 1, 2004·Cerebral Cortex·Sandra Bell-McGintyYaakov Stern
May 14, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael W L Chee, Wei Chieh Choo
Mar 31, 2005·Seminars in Neurology·Jeffrey S Durmer, David F Dinges
Jul 16, 2005·NeuroImage·Tor D WagerJohn Jonides
Jan 10, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Chiang-shan Ray LiRajita Sinha
Mar 3, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adam R Aron, Russell A Poldrack
May 16, 2006·Cerebral Cortex·Terence W PictonSusan Gillingham
Jul 11, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Y M Lisa ChuahMichael W L Chee
Oct 31, 2006·Journal of Cognitive Neuroscience·Darlene Floden, Donald T Stuss
Apr 6, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adam R AronRussell A Poldrack
Oct 19, 2007·Journal of Neurophysiology·Christopher D ChambersJason B Mattingley
Feb 5, 2008·Cerebral Cortex·Gui XueRussell A Poldrack
Mar 26, 2008·The Journal of Applied Psychology·James M LeBreton, Scott Tonidandel
May 17, 2008·Cerebral Cortex·D TomasiN D Volkow
Oct 7, 2008·Neuroscience and Biobehavioral Reviews·Christopher D ChambersMark A Bellgrove
Nov 16, 2010·Progress in Brain Research·William D S Killgore
Jan 5, 2011·NeuroImage·Danyang KongMichael W L Chee
Jan 29, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Adriana GalvánEdythe D London
May 25, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Dara G GhahremaniEdythe D London
Mar 26, 2013·Current Opinion in Neurobiology·Mathias BasnerDavid F Dinges
Jun 12, 2013·NeuroImage·Christopher L Asplund, Michael W L Chee
Jun 27, 2013·Human Brain Mapping·Weidong CaiHoi-Chung Leung
Jan 21, 2014·Trends in Cognitive Sciences·Adam R AronRussell A Poldrack
May 3, 2014·Behavioral Sleep Medicine·Erin L AlmklovOmar M Alhassoon

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Citations

Dec 8, 2019·American Journal of Respiratory and Critical Care Medicine·Christophe RaultXavier Drouot
Mar 18, 2021·Trends in Cognitive Sciences·Marcus O Harrington, Scott A Cairney
Jul 30, 2021·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Simin RahmanHrishikesh Kumar

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Methods Mentioned

BETA
SMA

Software Mentioned

Statistical Parametric Mapping SPM8
spmT

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