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Decreased H2 histamine response of granulocytes of asthmatic patients

The Journal of Clinical Investigation

Jun 1, 1977

W W Busse, J Sosman

Abstract

Increased bronchial sensitivity to inhaled histamine in asthma is well known. The mechanism of this increased bronchial sensitivity is not known nor has it been demonstrated that isolated cells respond abnormally to histamine. Polymorpho-nuclear leukocytes (PMNs) provide a homogeneous c...read more

Mentioned in this Paper

Neutrophil Band Cells
Histamine H2 Receptors
Kloromin
Histamine Receptor
Bronchitis
Exo-beta-D-Glucuronidase
Lysosomes
Asthma
Novodrin
Cyclic AMP, (R)-Isomer
Paper Details
References
  • References23
  • Citations32
123
  • References23
  • Citations32
1234

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Decreased H2 histamine response of granulocytes of asthmatic patients

The Journal of Clinical Investigation

Jun 1, 1977

W W Busse, J Sosman

PMID: 193871

DOI: 10.1172/jci108731

Abstract

Increased bronchial sensitivity to inhaled histamine in asthma is well known. The mechanism of this increased bronchial sensitivity is not known nor has it been demonstrated that isolated cells respond abnormally to histamine. Polymorpho-nuclear leukocytes (PMNs) provide a homogeneous c...read more

Mentioned in this Paper

Neutrophil Band Cells
Histamine H2 Receptors
Kloromin
Histamine Receptor
Bronchitis
Exo-beta-D-Glucuronidase
Lysosomes
Asthma
Novodrin
Cyclic AMP, (R)-Isomer

Feeds With Similar Papers

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Paper Details
References
  • References23
  • Citations32
123
  • References23
  • Citations32
1234

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